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Workers who joined the training programme were asked to undergo a new evaluation after 3 months. A total of 65 subjects without contact dermatitis were recruited as control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and one subjects from 143 workers, who were contacted, filled in the questionnaire. Sixty\u2010five of them followed the training course and underwent a new clinical evaluation with<jats:styled-content style=\"fixed-case\">TEWL<\/jats:styled-content> measurements.<\/jats:p><jats:p>Ongoing symptoms of subjects decreased from 60.0% to 42.3% 3 months after the training, and the subgroup which strictly adhered to the recommendations given achieved better results (61.9% of symptoms improvement when compared to 29.0% obtained in subjects with partial adhesion to the protocol). <jats:styled-content style=\"fixed-case\">TEWL<\/jats:styled-content> values changed from 21.3 \u00b1 9.6 to 18.6 \u00b1 7.2 g\/m\u00b2\/h (<jats:italic>P<\/jats:italic> = 0.001) on the hands and from 16.6 \u00b1 9.0 to 10.5 \u00b1 4.6 g\/m\u00b2\/h (<jats:italic>P<\/jats:italic> = 0.001) on the forearm, confirming the skin barrier improvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our secondary prevention intervention was effective, leading to a reduction in clinical signs of dermatitis. <jats:styled-content style=\"fixed-case\">TEWL<\/jats:styled-content> measurement is a useful tool to evaluate skin integrity, mostly in apparently healthy skin, which may have a compromised barrier function, resulting in an exacerbation of the dermatitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13947","type":"journal-article","created":{"date-parts":[[2016,8,25]],"date-time":"2016-08-25T08:18:03Z","timestamp":1472113083000},"page":"656-663","source":"Crossref","is-referenced-by-count":12,"title":["Effectiveness of a secondary prevention protocol for occupational contact dermatitis"],"prefix":"10.1111","volume":"31","author":[{"given":"M.","family":"Mauro","sequence":"first","affiliation":[{"name":"Clinical Unit of Occupational Medicine Department of Medical Sciences University of Trieste Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"De Giusti","sequence":"additional","affiliation":[{"name":"Clinical Unit of Occupational Medicine Department of Medical Sciences University of Trieste Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bovenzi","sequence":"additional","affiliation":[{"name":"Clinical Unit of Occupational Medicine Department of Medical Sciences University of Trieste Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Larese Filon","sequence":"additional","affiliation":[{"name":"Clinical Unit of Occupational Medicine Department of Medical Sciences University of Trieste Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004200050407"},{"key":"e_1_2_6_3_1","first-page":"128","article-title":"Epidemiology of occupational contact dermatitis in North Italian population","volume":"10","author":"Lodi A","year":"2000","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_4_1","first-page":"461","volume-title":"Medicina del lavoro. 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