{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:57:00Z","timestamp":1791280620388,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T00:00:00Z","timestamp":1487116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T00:00:00Z","timestamp":1487116800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,7]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Patients with hidradenitis suppurativa (\n HS<\/jats:styled-content>\n ) have an increased prevalence of traditional cardiovascular risk factors.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n Our aim was to investigate the association between subclinical atherosclerosis, detected by carotid ultrasound, and\n HS<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A prospective observation and analytical study assessing subclinical atherosclerosis using carotid ultrasound in patients with\n HS<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 62\n HS<\/jats:styled-content>\n patients and 62 matched controls were studied. Diabetes mellitus (22.6% vs. 6.5%,\n P<\/jats:italic>\n = 0.020), hypertension (41.9% vs. 12.9%,\n P<\/jats:italic>\n < 0.001) and metabolic syndrome (MetS) (38.7% vs. 8.1%,\n P<\/jats:italic>\n < 0.001) were more common in\n HS<\/jats:styled-content>\n patients. Elevated neutrophil\u2010to\u2010lymphocyte ratio (59.7% vs. 40.3%,\n P<\/jats:italic>\n = 0.031), high\u2010sensitivity C\u2010reactive protein (61.1 vs. 29.0%,\n P<\/jats:italic>\n < 0.001) and erythrocyte sedimentation rate (46.8% vs. 9.7%,\n P<\/jats:italic>\n < 0.001) were more frequent in patients with\n HS<\/jats:styled-content>\n . Subclinical atherosclerosis was present in 30.6% of\n HS<\/jats:styled-content>\n patients and in 16.1% of the controls subjects (\n P<\/jats:italic>\n = 0.06). After a logistic regression analysis, elevated age was associated with the presence of subclinical atherosclerosis (\n P<\/jats:italic>\n < 0.001), and\n HS<\/jats:styled-content>\n showed a tendency towards this association [adjusted\n OR<\/jats:styled-content>\n (95%\n CI<\/jats:styled-content>\n ) 3.8 (0.9\u201316.0),\n P<\/jats:italic>\n = 0.066]. This association was statistically significant between patients 40 years and older [\n OR<\/jats:styled-content>\n (95%\n CI<\/jats:styled-content>\n ) 4.9 (1.8\u201313.1)].\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Our clinical results indicate that patients with\n HS<\/jats:styled-content>\n have a higher prevalence of subclinical atherosclerosis than expected when correcting for traditional risk factors. The findings support the conclusions of previous epidemiological studies.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jdv.14076","type":"journal-article","created":{"date-parts":[[2016,12,2]],"date-time":"2016-12-02T07:44:26Z","timestamp":1480664666000},"page":"1229-1238","source":"Crossref","is-referenced-by-count":33,"title":["Assessment of subclinical atherosclerosis in hidradenitis suppurativa"],"prefix":"10.1111","volume":"31","author":[{"given":"J.C.","family":"Pascual","sequence":"first","affiliation":[{"name":"Department of Dermatology Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL\u2010FISABIO Foundation) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL\u2010FISABIO Foundation) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Corona","sequence":"additional","affiliation":[{"name":"Department of Neurology Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL\u2010FISABIO Foundation) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Hisp\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Dermatology Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL\u2010FISABIO Foundation) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Ramos","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL\u2010FISABIO Foundation) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"S\u00e1nchez\u2010Paya","sequence":"additional","affiliation":[{"name":"Epidemiology Unit Alicante University General Hospital Alicante Institute for Health and Biomedical Research (ISABIAL\u2010FISABIO Foundation) Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.B.","family":"Jemec","sequence":"additional","affiliation":[{"name":"Department of Dermatology Zealand University Hospital Roskilde Health Sciences Faculty University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1014163"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14024"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10254.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199901)42:1<51::AID-ANR7>3.0.CO;2-D"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-145-11-200612050-00022"},{"key":"e_1_2_6_7_1","first-page":"877","article-title":"Subclinical atherosclerosis in psoriatic arthritis: a case\u2010control study","volume":"35","author":"Eder L","year":"2008","journal-title":"J Rheumatol"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03481.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1882"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.6.2.131"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032804"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199901073400103"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.03.002"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.4.841"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000431175"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/circ.106.25.3143"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/08037051.2014.868629"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000343145"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2014.10.008"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.628875"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2005.03.004"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200112)44:12<2737::AID-ART460>3.0.CO;2-#"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14075"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2015.03.009"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1159\/000446021"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.6264"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.03.025"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket454"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.14076","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.14076","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.14076","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.14076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:41:55Z","timestamp":1791279715000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.14076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,15]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1111\/jdv.14076"],"URL":"https:\/\/doi.org\/10.1111\/jdv.14076","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,15]]}}}