{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T22:11:40Z","timestamp":1779315100580,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T00:00:00Z","timestamp":1489017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005614","name":"Biogen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005614","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006436","name":"Celgene","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006436","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004312","name":"Eli Lilly and Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Inequality between age groups has been demonstrated in the prescription of biologics, yet systematic real\u2010world data about age\u2010related differences in psoriasis care are missing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate disparities in psoriasis characteristics by age groups and to identify potential impact on psoriasis health care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Data analysis included 3615 patients from the German psoriasis registry PsoBest, which observes adult patients with moderate\u2010to\u2010severe psoriasis or psoriatic arthritis (PsA) on systemic treatment over a time period of 10 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>With 2376 participants (65.7%), the majority of patients was assigned to the age group 35\u201364, followed by 776 (21.4%) and 463 (12.8%) for the age groups 18\u201334 and 65+, respectively. Psoriasis vulgaris was the most frequent form of psoriasis with nearly 90% patients affected. Appearance of psoriasis forms did not differentiate significantly between the age groups except for erythrodermic psoriasis, which was more frequent in the elderly than in patients aged 35\u201364 (1.9%, <jats:italic>P<\/jats:italic> \u2264 0.048). Nail psoriasis appeared significantly more often in patients aged 35\u201364 (55.5%, <jats:italic>P<\/jats:italic> \u2264 0.001) and also showed the highest number of nails involved (6.9 \u00b1 3.3). PsA was less frequent in the age group 18\u201334 (9.5%, <jats:italic>P<\/jats:italic> \u2264 0.001). This group showed the highest rate of scalp psoriasis (85.8%) compared to the elder age groups (<jats:italic>P<\/jats:italic> \u2264 0.001). Biologicals were used significantly less in younger patients (16.2%) compared to the age groups 35\u201364 (23.9%, <jats:italic>P<\/jats:italic> \u2264 0.001) and 65+ (21.8%, <jats:italic>P<\/jats:italic> \u2264 0.042).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Middle\u2010aged patients show higher rates of PsA and nail psoriasis, which may explain age\u2010dependent disparities in health care including the use of systemic treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.14115","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T02:52:44Z","timestamp":1484275964000},"page":"870-875","source":"Crossref","is-referenced-by-count":28,"title":["The impact of age on psoriasis health care in Germany"],"prefix":"10.1111","volume":"31","author":[{"given":"A.","family":"Trettel","sequence":"first","affiliation":[{"name":"Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center 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