{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T20:05:42Z","timestamp":1774987542936,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T00:00:00Z","timestamp":1488153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008271","name":"LEO Pharma Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008271","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patient\u2010reported outcome measures are very important outcomes. For specific diseases, health\u2010related quality of life\u2010instruments (<jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL) are increasingly used to provide data on patients\u2019 overall perceptions of the course of a given disease. Actinic keratoses (<jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>s) are common keratotic lesions that occur on chronically sunlight\u2010exposed skin. Only few studies regarding <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL in <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>s have been made.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>In order to be able to compare <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL among different countries and cultures, we aimed to translate and validate the Actinic Keratosis Quality of Life (<jats:styled-content style=\"fixed-case\">AKQ<\/jats:styled-content>oL) questionnaire into Spanish and quantify the impairment caused by <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>s in Spanish patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">AKQ<\/jats:styled-content>oL was translated. Then, 15 patients with <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>s were interviewed to ensure cultural adaption before it was tested in one hundred patients with <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> lesions at the Melanoma Unit of Hospital Clinic in Barcelona.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Validation showed high interitem correlations, as well as a high correlation of each item and the total score. Internal consistency (Cronbach's coefficient alpha) was also high at 0.91 and an alpha value of 0.90 at retest. The test\u2013retest correlation was 0.96, and the intraclass coefficient was 0.98.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presented data support the <jats:styled-content style=\"fixed-case\">AKQ<\/jats:styled-content>oL Spanish version as a valid and reliable <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL questionnaire for the description of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>\u2010related QoL and may provide a method for comparison of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> specific QoL between different cultures and countries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.14127","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T22:10:07Z","timestamp":1484950207000},"page":"986-991","source":"Crossref","is-referenced-by-count":9,"title":["Spanish version of the Actinic Keratosis Quality of Life 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