{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:05:00Z","timestamp":1782835500174,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,3,13]],"date-time":"2017-03-13T00:00:00Z","timestamp":1489363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Unilesional mycosis fungoides (UMF) and pagetoid reticulosis (PR) are variants of mycosis fungoides. Conventional therapy comprises surgical excision or radiotherapy, which may be associated with long\u2010term side effects, especially when the lesion is located at a special site like the palms and soles. Therefore, alternative treatment options are needed to treat solitary lesions in the case of UMF or PR. Recently, topical photodynamic therapy (PDT) has been described to be an efficient and non\u2010invasive therapeutical option with excellent clinical outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study was to report a 43\u2010year\u2010old woman with plantar UMF treated successfully with PDT, and to compare our findings with the data on PDT in UMF and PR reported in the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The literature was analysed for articles on UMF and PR, respectively, treated with topical PDT. Various parameters including form of PDT and response to treatment were analysed and compared with our case.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 24 patients were documented with 24 lesions treated with PDT, either using aminolevulinic acid (ALA) or methylaminolevulinate (MAL). In average, a single lesion was treated 4 times with PDT. In 21 cases (88%), complete response could be achieved, whereas three cases (13%) showed partial remission. None of the cases showed stable or progressive disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PDT is a safe, efficient and non\u2010invasive therapeutical approach for the treatment of UMF and PR. It has no long\u2010standing adverse events and therefore is of high therapeutic value especially in cases of UMF and PR located at special sites like the palms and soles. We propose to include topical PDT as therapeutic option for the treatment of UMF and PR in future guidelines on the management MF.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.14160","type":"journal-article","created":{"date-parts":[[2017,2,7]],"date-time":"2017-02-07T02:42:58Z","timestamp":1486435378000},"page":"1633-1637","source":"Crossref","is-referenced-by-count":17,"title":["Unilesional plantar mycosis fungoides treated with topical photodynamic therapy \u2013 case report and review of the literature"],"prefix":"10.1111","volume":"31","author":[{"given":"F.","family":"Kaufmann","sequence":"first","affiliation":[{"name":"Dermatology Practice Schaffhauserplatz Zurich Switzerland"},{"name":"Department of Dermatology University Hospital Zurich Zurich Switzerland"},{"name":"Kempf und Pfaltz Histologische Diagnostik Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Kettelhack","sequence":"additional","affiliation":[{"name":"Dermatology Practice Schaffhauserplatz Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Hilty","sequence":"additional","affiliation":[{"name":"Dermapoint Schaan The Principality of Liechtenstein"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Kempf","sequence":"additional","affiliation":[{"name":"Dermatology Practice Schaffhauserplatz Zurich Switzerland"},{"name":"Department of Dermatology University Hospital Zurich Zurich Switzerland"},{"name":"Kempf und Pfaltz Histologische Diagnostik Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,13]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90140-3"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880088"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00218-1"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)91413-7"},{"key":"e_1_2_5_7_1","first-page":"75","article-title":"Unilesional mycosis fungoides treated with photodynamic therapy. 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