{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:57:46Z","timestamp":1791280666535,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T00:00:00Z","timestamp":1492732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T00:00:00Z","timestamp":1492732800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Sparse information is available concerning mental health issues in psoriasis, psoriatic arthritis (PsA) and ankylosing spondylitis (\n                      <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>\n                      ) patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To estimate risk of depression, suicidal ideation and suicide attempt in patients with psoriasis, PsA and\n                      <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>\n                      , respectively, compared with the general population.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This population\u2010based cohort study analysed 36 214 psoriasis patients, 5138 PsA patients and 1878\n                      <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>\n                      patients who were frequency\u2010matched with a general population cohort. Annual incidence rate of depression, suicidal ideation and suicide attempt was calculated separately for psoriasis, PsA and\n                      <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was an increased risk of depression in the three cohorts; adjusted\n                      <jats:styled-content style=\"fixed-case\">IRR<\/jats:styled-content>\n                      : psoriasis, 1.14 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      , 1.11, 1.17); PsA, 1.22 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      , 1.16, 1.29);\n                      <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>\n                      , 1.34 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      , 1.23, 1.47). There was no significantly increased risk for suicidal ideations or suicide attempt among psoriasis, PsA or\n                      <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>\n                      patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Limitations<\/jats:title>\n                    <jats:p>Patients were not excluded if previously diagnosed with depression, suicidal ideation or suicide attempt. Suicide attempt and completed suicide analyses were not adjusted for presence of depression. Use of systemic psoriasis treatment to measure severe psoriasis could lead to psoriasis severity misclassification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The risk of depression, but not suicidal ideation or suicide attempt, was significantly increased in patients with psoriasis, PsA and\n                      <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.14175","type":"journal-article","created":{"date-parts":[[2017,2,18]],"date-time":"2017-02-18T15:22:46Z","timestamp":1487431366000},"page":"1168-1175","source":"Crossref","is-referenced-by-count":113,"title":["The risk of depression, suicidal ideation and suicide attempt in patients with psoriasis, psoriatic arthritis or ankylosing spondylitis"],"prefix":"10.1111","volume":"31","author":[{"given":"J.J.","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Dermatology Kaiser Permanente Los Angeles Medical Center Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.B.","family":"Penfold","sequence":"additional","affiliation":[{"name":"Group Health Research Institute Group Health Cooperative Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Primatesta","sequence":"additional","affiliation":[{"name":"Quantitative Safety &amp; 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