{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T02:47:03Z","timestamp":1781750823379,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T00:00:00Z","timestamp":1499040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009754","name":"Galderma","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009754","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acne is a chronic dermatological disease predominantly afflicting young adults and is often associated with the development of scars. Acne scarring is usually avoidable when acne is managed early and effectively. However, acne patients often fail to seek early treatment. New and innovative tools to raise awareness are needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study presents the development and assessment of a tool aiming to assess the risk of atrophic acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic literature review of clinical risk factors for acne scars, a Delphi\u2010like survey of dermatological experts in acne and secondary data analysis, were conducted to produce an evidence\u2010based risk assessment tool. The tool was assessed both with a sample of young adults with and without scars and was assessed via a database cross\u2010validation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A self\u2010administered tool for risk assessment of developing atrophic acne scars in young adults was developed. It is a readily comprehensible and practical tool for population education and for use in medical practices. It comprises of four risk factors: worst ever severity of acne, duration of acne, family history of atrophic acne scars and lesion manipulation behaviours. It provides a dichotomous outcome: lower vs. higher risk of developing scars, thereby categorizing nearly two\u2010thirds of the population correctly, with sensitivity of 82% and specificity of 43%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present tool was developed as a response to current challenges in acne scar prevention. A potential benefit is to encourage those at risk to self\u2010identify and to seek active intervention of their acne. In clinical practice, we expect this tool may help clinicians identify patients at risk of atrophic acne scarring and underscore their requirement for rapid and effective acne treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.14325","type":"journal-article","created":{"date-parts":[[2017,5,12]],"date-time":"2017-05-12T16:03:13Z","timestamp":1494604993000},"page":"1547-1554","source":"Crossref","is-referenced-by-count":44,"title":["Development of an atrophic acne scar risk assessment tool"],"prefix":"10.1111","volume":"31","author":[{"given":"J.","family":"Tan","sequence":"first","affiliation":[{"name":"Western University Windsor Campus Windsor ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Thiboutot","sequence":"additional","affiliation":[{"name":"Department of Dermatology Pennsylvania State University College of Medicine Hershey PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Gollnick","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Dermatologie und Venerologie Otto\u2010von\u2010Guericke Universit\u00e4t Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kang","sequence":"additional","affiliation":[{"name":"Johns Hopkins School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Layton","sequence":"additional","affiliation":[{"name":"Department of Dermatology Harrogate and District NHS Foundation Trust Harrogate UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.","family":"Leyden","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Torres","sequence":"additional","affiliation":[{"name":"Department of Dermatology Juarez Hospital Mexico City Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Guillemot","sequence":"additional","affiliation":[{"name":"Amaris London UK"},{"name":"Universidad San Francisco de Quito (USFQ) School of Medicine Quito Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Dr\u00e9no","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nantes University Hospital Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200809050-00001"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000067817"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12149"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2011.11.001"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962012000600007"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02768.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13675"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.019"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.12.037"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01200.x"},{"key":"e_1_2_5_12_1","unstructured":"Dr\u00e9noB LaytonA BettoliV Torres LozadaV KangS Global Alliance to Improve Outcomes in Acne.P024: Evaluation of the prevalence risk factors clinical characteristics and burden of acne scars among active acne patients who have consulted a dermatologist in Brazil France and the USA. In 23rd EADV Congress;2014;Amsterdam The Netherlands."},{"key":"e_1_2_5_13_1","unstructured":"BourdesV FaureC PetitLet al.Natural history of acne lesions and atrophic acne scars within a 6\u2010month study period. In World Congress of Dermatology;2015;Vancover Canada."},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.167272"},{"key":"e_1_2_5_15_1","article-title":"The psychosocial impact of post\u2010acne scarring","volume":"23","author":"Fried R","year":"2015","journal-title":"Dermatologist"},{"key":"e_1_2_5_16_1","unstructured":"CzernielewskiJ Dr\u00e9noB LaytonAet al.Evaluation of the prevalence risk factors clinical characteritics and burden of acne scars among active acne patients in Brazil France and the USA. In World Congress of Dermatology;2015;Vancover Canada."},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-016-0113-x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12204"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.2015.0129"},{"key":"e_1_2_5_20_1","first-page":"1","article-title":"The Delphi technique: making sense of consensus","volume":"12","author":"Hsu CC","year":"2007","journal-title":"Pract Assess Res Eval"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1576\/toag.7.2.120.27071"},{"key":"e_1_2_5_22_1","first-page":"627","article-title":"Receiver Operating Characteristic (ROC) curve analysis for medical diagnostic test evaluation","volume":"4","author":"Hajian\u2010Tilaki K","year":"2013","journal-title":"Caspian J Intern Med"},{"key":"e_1_2_5_23_1","article-title":"Identifying persons at highest risk of melanoma using self\u2010assessed risk factors","volume":"2","author":"Williams L","year":"2011","journal-title":"J Clin Exp Dermatol Res"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-11-123"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0b013e328333d113"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.34-11-479"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2005.03.004"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670060015008"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.14325","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.14325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T23:52:47Z","timestamp":1695513167000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.14325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,3]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1111\/jdv.14325"],"URL":"https:\/\/doi.org\/10.1111\/jdv.14325","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,3]]}}}