{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:52:04Z","timestamp":1783021924285,"version":"3.54.6"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,8,16]],"date-time":"2017-08-16T00:00:00Z","timestamp":1502841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>It has been reported that patients with psoriasis are at increased risk for developing lymphoma including cutaneous T\u2010cell lymphomas (<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>). However, the comorbidity and the histopathologic correlation of psoriasis and mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>) have been less studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study was to investigate the relation between MF and psoriasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed and re\u2010evaluated all <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> cases diagnosed and followed in a 16\u2010year period who carried both <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> and psoriasis diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010one of 321 <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> patients was the rate of psoriasis\u2019 comorbidity according to medical records. Twenty\u2010five patients (7.8%) finally met the inclusion criteria. The rest were excluded due to inadequate evidence. Twenty patients had psoriatic lesions at the time of <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> diagnosis. In 23 patients, there was histological confirmation of both diseases. Six patients (24%) were diagnosed with folliculotropic <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>, two were diagnosed with pustular psoriasis, and six patients were affected by palmoplantar and nail psoriasis. In four patients, there was a very short time interval between <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> and psoriasis diagnosis. Fourteen patients with psoriasis had been previously treated with immunomodulatory regimens. Interestingly, in eight patients, typical histological findings of both diseases were detected in the same biopsy specimen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results support the opinion that the association between psoriasis and <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> does exist. It is most possibly related to the chronic lymphocyte stimulation that occurs during psoriasis that eventually leads to a dominant clone and the evolution to <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>. Our study suggests that apart from cases of early <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>, which are being indeed misdiagnosed as psoriasis, there is another group of patients, where psoriasis truly coexists with \u2013 or even progresses to \u2013 <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.14365","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T07:23:46Z","timestamp":1496129026000},"page":"1848-1852","source":"Crossref","is-referenced-by-count":19,"title":["Psoriasis in patients with mycosis fungoides: a clinicopathological study of 25 patients"],"prefix":"10.1111","volume":"31","author":[{"given":"V.","family":"Nikolaou","sequence":"first","affiliation":[{"name":"Cutaneous Lymphoma Clinic \u201cAndreas Sygros\u201d Hospital for Skin Diseases Athens 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