{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:50:26Z","timestamp":1792291826617,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T00:00:00Z","timestamp":1505088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T00:00:00Z","timestamp":1505088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      More than 25% of the adult European population suffers from contact allergy, with fragrance substances recognized as one of the main causes. Since 2005, 26 fragrance contact allergens have been mandatory to label in cosmetic products within the\n                      <jats:styled-content style=\"fixed-case\">EU<\/jats:styled-content>\n                      if present at 10\u00a0ppm or above in leave\u2010on and 100\u00a0ppm or above in wash\u2010off cosmetics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine exposure, based on ingredient labelling, to the 26 fragrances in a sample of 5588 fragranced cosmetic products.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The investigated products were identified through a novel, non\u2010profit smartphone application (app), designed to provide information to consumers about chemical substances in cosmetic products. Products registered through the app between December 2015 and October 2016 were label checked according to International Nomenclature of Cosmetic Ingredients (\n                      <jats:styled-content style=\"fixed-case\">INCI<\/jats:styled-content>\n                      ) for the presence of the 26 fragrance substances or the wording \u2018fragrance\/parfum\/aroma\u2019.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The largest product categories investigated were \u2018cream, lotion and oil\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a01192), \u2018shampoo and conditioner\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0968) and \u2018deodorants\u2019 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0632). Among cosmetic products labelled to contain at least one of the 26 fragrances, 85.5% and 73.9% contained at least two and at least three of the 26 fragrances, respectively. Linalool (49.5%) and limonene (48.5%) were labelled most often among all investigated products. Hydroxyisohexyl 3\u2010cyclohexene carboxaldehyde (\n                      <jats:styled-content style=\"fixed-case\">HICC<\/jats:styled-content>\n                      \/Lyral\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ) was found in 13.5% of deodorants. Six of the 26 fragrance substances were labelled on less than one per cent of all products, including the natural extracts\n                      <jats:italic>Evernia furfuracea<\/jats:italic>\n                      (tree moss) and\n                      <jats:italic>Evernia prunastri<\/jats:italic>\n                      (oak moss). A total of 329 (5.9%) products had one or more of the 26 fragrance substances labelled but did not have \u2018parfum\/fragrance\/aroma\u2019 listed on the label.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Consumers are widely exposed to, often multiple, well\u2010established fragrance contact allergens through various cosmetic products intended for daily use. Several fragrance substances that are common causes of contact allergy were rarely labelled in this large sample of cosmetic products.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.14513","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T12:36:34Z","timestamp":1502368594000},"page":"79-85","source":"Crossref","is-referenced-by-count":58,"title":["Fragrance contact allergens in 5588 cosmetic products identified through a novel smartphone application"],"prefix":"10.1111","volume":"32","author":[{"given":"N.H.","family":"Bennike","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy National Allergy Research Centre Herlev\u2010Gentofte Hospital University of Copenhagen Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.B.","family":"Oturai","sequence":"additional","affiliation":[{"name":"Danish Consumer Council THINK Chemicals Copenhagen K Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Danish Consumer Council THINK Chemicals Copenhagen K Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.S.","family":"Kirkeby","sequence":"additional","affiliation":[{"name":"Danish Consumer Council THINK Chemicals Copenhagen K Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"J\u00f8rgensen","sequence":"additional","affiliation":[{"name":"Danish Consumer Council THINK Chemicals Copenhagen K Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.B.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Danish Consumer Council THINK Chemicals Copenhagen K Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Zachariae","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Herlev\u2010Gentofte Hospital University of Copenhagen Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy National Allergy Research Centre Herlev\u2010Gentofte Hospital University of Copenhagen Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14167"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02070.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12128"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12117"},{"key":"e_1_2_6_6_1","unstructured":"SCCNFP\/0017\/98 Opinion concerning Fragrance allergy in consumers1999. 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