{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:50:52Z","timestamp":1791283852966,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T00:00:00Z","timestamp":1506038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T00:00:00Z","timestamp":1506038400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Negative pressure wound therapy (\n                      <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>\n                      ) is an established treatment modality in dermatologic surgery, but proof of evidence for efficacy is inconclusive.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To evaluate patient characteristics, treatment modalities and outcomes in a single dermatosurgery centre with\n                      <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>\n                      applied over chronic and acute surgical wounds.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Of all surgical patients between 2008 and 2015, we selected those who were treated and hospitalized due to\n                      <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>\n                      for treatment of acute and chronic wounds. The medical records of 188 patients were retrospectively evaluated and statistically calculated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Method of surgical defect closure depends significantly on localization of the surgical defect, cardiovascular comorbidity and age. Hence, outcome depends significantly on the surgical situation that indexes\n                      <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>\n                      , the underlying diagnosis and the vacuum system used, but is not associated with distinct treatment modalities or gender of the patients. Hospitalization significantly depends on the vacuum system used, surgical situation that indexes\n                      <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>\n                      and underlying diagnoses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>\n                      has a fixed role in distinct, well\u2010defined clinical indications in dermatosurgery as the treatment of acute surgical wounds, fixation of skin grafts and treatment of skin substitutes, as well as an important treatment option for refractory, superinfected chronic wounds in dermatologic patients.\n                    <\/jats:p>\n                  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