{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:38:32Z","timestamp":1792532312260,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T00:00:00Z","timestamp":1507593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n \n Overweight is a well\u2010established risk factor for hidradenitis suppurativa (\n HS<\/jats:styled-content>\n ). In this cross\u2010sectional study, we compare\n HS<\/jats:styled-content>\n patients with a high body mass index (\n BMI<\/jats:styled-content>\n ) with\n HS<\/jats:styled-content>\n patients with a low\n BMI<\/jats:styled-content>\n to investigate differences in disease characteristics.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and method<\/jats:title>\n \n Patients were recruited from 17 dermatological centres from four continents. A total of 246 patients with a\n BMI<\/jats:styled-content>\n below 25 were compared to 205 patients with a\n BMI<\/jats:styled-content>\n of above 35.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Patients with a high\n BMI<\/jats:styled-content>\n suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient\u2010reported severity (PRS),\n P<\/jats:italic>\n \u00a0<\u00a00.001 for all). There was no difference in smoking (\n P<\/jats:italic>\n \u00a0=\u00a00.783) nor in family history (\n P<\/jats:italic>\n \u00a0=\u00a00.088).\u00a0In both low and high\n BMI<\/jats:styled-content>\n patients, early onset of\n HS<\/jats:styled-content>\n was a predictor of positive family history (\n P<\/jats:italic>\n \u00a0<\u00a00.001, for each). For low\n BMI<\/jats:styled-content>\n patients, an increase in\n BMI<\/jats:styled-content>\n significantly increased PRS (\n P<\/jats:italic>\n \u00a0<\u00a00.001). For patients with a high\n BMI<\/jats:styled-content>\n , number of pack\u2010years significantly increased PRS (\n P<\/jats:italic>\n \u00a0=\u00a00.001). Cluster analysis of eruption patterns was location specific for low\n BMI<\/jats:styled-content>\n patients but severity specific for high\n BMI<\/jats:styled-content>\n patients.\n <\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n \n Patients with a low and high BMI could represent two clinically different subtypes. We suggest a non\u2010linear relationship between\n BMI<\/jats:styled-content>\n and impact of\n HS<\/jats:styled-content>\n . As patients go from a low\n BMI<\/jats:styled-content>\n patient to a high\n BMI<\/jats:styled-content>\n patient (or from high to low), eruption patterns and risk factors may change.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jdv.14599","type":"journal-article","created":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T03:02:53Z","timestamp":1505962973000},"page":"307-312","source":"Crossref","is-referenced-by-count":63,"title":["Low and high body mass index in hidradenitis suppurativa patients\u2014different subtypes?"],"prefix":"10.1111","volume":"32","author":[{"given":"P.","family":"Theut Riis","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Zealand Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M.","family":"Saunte","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Zealand Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Benhadou","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hopital Erasme Universit\u00e9 Libre de Bruxelles Bruxelles Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"del Marmol","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hopital Erasme Universit\u00e9 Libre de Bruxelles Bruxelles Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Guillem","sequence":"additional","affiliation":[{"name":"Clinique du Val d'Ouest Ecully France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"El\u2010Domyati","sequence":"additional","affiliation":[{"name":"Department of Dermatology Minia University Al\u2010Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Abdel\u2010Wahab","sequence":"additional","affiliation":[{"name":"Department of Dermatology Minia University Al\u2010Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Antoniou","sequence":"additional","affiliation":[{"name":"Department of Dermatology Andreas Sygros Hospital University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Dessinioti","sequence":"additional","affiliation":[{"name":"Department of Dermatology Andreas Sygros Hospital University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"G\u00fcrer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Beksa\u00e7","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Szepietowski","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology Wroclaw Medical University Wroclaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Matusiak","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology Wroclaw Medical University Wroclaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Emtestam","sequence":"additional","affiliation":[{"name":"Unit of Infection and Dermatology Department of Medicine Huddinge at Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Lapins","sequence":"additional","affiliation":[{"name":"Unit of Infection and Dermatology Department of Medicine Huddinge at Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Riad","sequence":"additional","affiliation":[{"name":"Hamad medical corporation Doha Quatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Doss","sequence":"additional","affiliation":[{"name":"Department of Dermatology Military Hospital of Tunis University Tunis El Manar Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.F.","family":"Massa","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Dermatol\u00f3gica Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Hamzavi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Henry Ford Hospital Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Nicholson","sequence":"additional","affiliation":[{"name":"Department of Dermatology Henry Ford Hospital Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Dolenc\u2010Voljc","sequence":"additional","affiliation":[{"name":"Department of Dermatovenereology University Medical Centre Ljubljana Ljubljana Slovenia"},{"name":"Faculty of Medicine University of Ljubljana Ljubljana Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.H.","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory of Cutaneous Aging and Hair Research Biomedical Research Institute Seoul National University Hospital Seoul Korea"},{"name":"Institute of Human\u2010Environment Interface Biology Seoul National University College of Medicine Seoul 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