{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:03:58Z","timestamp":1790949838855,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T00:00:00Z","timestamp":1520553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009947","name":"Merck Sharp and Dohme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009947","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Dermatologists are recommended to ask psoriasis patients about musculoskeletal complaints to allow early detection and treatment of psoriatic arthritis (PsA). Screening tools have been developed to help identify patients warranting further rheumatologic assessment, but evidence suggests room for improvement in their diagnostic value and ease of use for outpatient practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To develop and internally validate a brief tool for dermatologists to screen patients to refer to a rheumatologist for PsA diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>After the literature review, 23 items were selected, covering pain at various locations and inflammatory signs of PsA. The validation study was conducted in medically diagnosed psoriasis patients consecutively recruited between 2012 and 2014 (Saint Joseph Hospital, Paris, France). Patients were enrolled by a dermatologist who helped to complete the questionnaire. Diagnosis of PsA was established by a rheumatologist based on <jats:styled-content style=\"fixed-case\">CASPAR<\/jats:styled-content> criteria. Multivariate logistic regression models were performed to build the scale, assessing discrimination through sensitivity, specificity and area under the <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content> curve (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>). Final model was internally validated using bootstrapping techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and sixty\u2010eight patients were recruited, of whom nine were excluded for known PsA and 21 did not attend the rheumatologist consultation. Of 137 included patients (median age 43 years, 59.6% men), 21 (15.3%) had a PsA diagnosis. Final regression model retained four independent items, including evocative signs of dactylitis, inflammatory heel pain, bilateral buttock pain and peripheral joint pain with swelling in patients aged &lt;50. A total score (the <jats:styled-content style=\"fixed-case\">PURE<\/jats:styled-content>\u20104) was computed (0\u20134 points) that demonstrated excellent discriminative power (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content> = 87.6%; Sensitivity = 85.7% and Specificity = 83.6% at the threshold of \u22651\/4 points), with no evidence for over\u2010optimism in bootstrapped internal validation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings demonstrate the good diagnostic properties of a new screening scale using only four easy\u2010to\u2010collect items. If confirmed in other populations, it may prove useful in outpatient dermatology clinics for triage of psoriasis patients requiring further assessment by the rheumatologist.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.14861","type":"journal-article","created":{"date-parts":[[2018,2,11]],"date-time":"2018-02-11T14:16:40Z","timestamp":1518358600000},"page":"1950-1953","source":"Crossref","is-referenced-by-count":42,"title":["Psoriatic arthritis screening by the dermatologist: development and first validation of the \u2018<scp>PURE<\/scp>\u20104 scale\u2019"],"prefix":"10.1111","volume":"32","author":[{"given":"E.","family":"Audureau","sequence":"first","affiliation":[{"name":"Department of Public Health Henri Mondor Hospital Universit\u00e9 Paris Est Cr\u00e9teil EA 7376 \u2013 CEpiA Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Roux","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Saint Joseph Hospital Paris 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France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Hilliquin","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Sud Francilien Hospital Corbeil Essonnes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Jullien","sequence":"additional","affiliation":[{"name":"Department of Dermatology Edouard Herriot Hospital University Claude Bernard Lyon\u20101 University of Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Liot\u00e9","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Lariboisi\u00e8re Hospital University Paris Diderot Sorbonne Paris Cit\u00e9 Inserm UMR 1132 Bioscar Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Passeron","sequence":"additional","affiliation":[{"name":"Department of Dermatology INSERM U1065 \u00e9quipe 12, C3M Nice 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