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Members of the <jats:styled-content style=\"fixed-case\">EADV TF<\/jats:styled-content> on QoL and <jats:styled-content style=\"fixed-case\">PO<\/jats:styled-content> decided to detect which acne treatment has the best influence on <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL of acne patients. A new literature search was organized to find publications on acne treatment where the <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL of patients was assessed as an outcome measure. From 186 papers with <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL assessment, 37 papers were included for further analysis. Our results revealed that oral isotretinoin had the best influence on <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL of acne patients. Several other treatment methods also showed good effects on the <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL of acne patients. Oral isotretinoin and norethindrone acetate\/ethinyl estradiol, topical clindamycin phosphate\/benzoyl peroxide and adapalene\/benzoyl peroxide showed significantly better effect on <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL than placebo. There is limited number of the high\u2010quality studies on acne treatment where <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL was assessed. Dermatology\u2010specific and acne\u2010specific instruments showed much better sensitivity to successful therapeutic intervention than generic <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL instruments. The most frequently used <jats:styled-content style=\"fixed-case\">HRQ<\/jats:styled-content>oL instrument was the Dermatology Life Quality Index questionnaire.<\/jats:p>","DOI":"10.1111\/jdv.15048","type":"journal-article","created":{"date-parts":[[2018,5,5]],"date-time":"2018-05-05T11:37:03Z","timestamp":1525520223000},"page":"1410-1419","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Which acne treatment has the best influence on health\u2010related quality of life? 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