{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:51:10Z","timestamp":1772160670183,"version":"3.50.1"},"reference-count":4,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T00:00:00Z","timestamp":1531785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002429","name":"Amgen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002429","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2018,12]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Hidradenitis suppurativa clinical response (Hi\n SCR<\/jats:styled-content>\n ) is a validated clinical end point for measuring response to treatment in patients with hidradenitis suppurativa (\n HS<\/jats:styled-content>\n ). Previous studies have reported on the validity, responsiveness and meaningfulness of the Hi\n SCR<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n To evaluate the Hi\n SCR<\/jats:styled-content>\n for inter\u2010 and intrarater reliability characteristics.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A stand\u2010alone, two\u2010site, prospective, non\u2010interventional observational study consisted of 22 patients, with self\u2010reported severity between mild, moderate and severe\n HS<\/jats:styled-content>\n . The Patient Global Impression of Change (\n PGI<\/jats:styled-content>\n \u2010C) scale was completed by patients at Timepoint 2. Descriptive statistics of Hurley Stage, total abscesses, total draining fistulas, total inflammatory nodules and total\n AN<\/jats:styled-content>\n count (sum of inflammatory nodules and lesions) were reported at two timepoints. Inter\u2010rater reliability and intrarater reliability for the\n HS<\/jats:styled-content>\n lesion count tool were evaluated at two timepoints (baseline and Day 7) using the\n HS<\/jats:styled-content>\n lesion count tool. Intraclass correlation (\n ICC<\/jats:styled-content>\n ) coefficients of lesion counts were calculated to evaluate inter\u2010 and intrarater reliability of lesion counts between pairs of dermatologists.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The majority of patients demonstrated either no change or minimally worse\n PGI<\/jats:styled-content>\n \u2010C in\n HS<\/jats:styled-content>\n scores. Descriptive statistics were similar between rater groups and timepoints assessed. Inter\u2010rater\n ICC<\/jats:styled-content>\n coefficients for abscess count at Timepoints 1 and 2 were 0.38 and 0.67. The\n ICC<\/jats:styled-content>\n coefficients for draining fistula and\n AN<\/jats:styled-content>\n count were \u22650.61 at both timepoints. In an exploratory model,\n ICC<\/jats:styled-content>\n coefficients were \u22650.68 for all evaluated lesion counts. The test\u2013retest reliability using\n ICC<\/jats:styled-content>\n coefficients was \u22650.70 for total abscess, draining fistula, inflammatory nodule and\n AN<\/jats:styled-content>\n count.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The\n HS<\/jats:styled-content>\n lesion count tool had an acceptable inter\u2010 and intrarater reliability, indicating that Hi\n SCR<\/jats:styled-content>\n has a strong degree of reproducibility and consistency in the evaluation of patients with\n HS<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jdv.15163","type":"journal-article","created":{"date-parts":[[2018,6,30]],"date-time":"2018-06-30T02:58:02Z","timestamp":1530327482000},"page":"2254-2256","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Reliability of the hidradenitis suppurativa clinical response in the assessment of patients with hidradenitis suppurativa"],"prefix":"10.1111","volume":"32","author":[{"given":"A.B.","family":"Kimball","sequence":"first","affiliation":[{"name":"Department of Dermatology Harvard Medical School Beth Israel Deaconess Medical Center Boston MA USA"},{"name":"Analysis Group Inc Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ganguli","sequence":"additional","affiliation":[{"name":"AbbVie Inc North Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fleischer","sequence":"additional","affiliation":[{"name":"AbbVie Inc North Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,17]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-33101-8_8"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.06.020"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13270"},{"key":"e_1_2_4_5_1","unstructured":"European Medicines Agency Committee for Medicinal Products for Human Use. Assessment report. EMA\/CHMP\/364731\/2015. June 25 2015."}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.15163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.15163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:17:49Z","timestamp":1694737069000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.15163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,17]]},"references-count":4,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1111\/jdv.15163"],"URL":"https:\/\/doi.org\/10.1111\/jdv.15163","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.733534772.793577150","asserted-by":"object"}]},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,17]]},"assertion":[{"value":"2018-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}