{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:11:46Z","timestamp":1790230306442,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T00:00:00Z","timestamp":1537660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sexual health is frequently affected by chronic diseases but has been poorly investigated in patients with atopic dermatitis (<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the risk factors for impaired sexual desire and its relationship with the burden and quality of life of patients with <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multicentre prospective transversal study in patients with <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>. Socio\u2010demographic and clinical data were obtained from all patients using a specifically developed questionnaire. In addition, patients were asked to answer validated scales, that is <jats:styled-content style=\"fixed-case\">ABS<\/jats:styled-content>\u2010A, <jats:styled-content style=\"fixed-case\">DLQI<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> SF<\/jats:styled-content>\u201012 and <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u20105D.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1024 patients participated in the study. Severity of <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>, sites involved and treatment type was found to negatively impact the sexual desire of patients and their partners. In addition, the involvement of the genital and visible areas was associated with a higher burden and more significant alterations in quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this study are substantial and clearly demonstrate the deep impact of <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> on sexual health, its relationship with disease\u2010related burden and alterations to quality of life. Psychosociological as well as neurosensory phenomena could help to understand these data.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.15223","type":"journal-article","created":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T19:10:28Z","timestamp":1535656228000},"page":"428-432","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["The impact of atopic dermatitis on sexual health"],"prefix":"10.1111","volume":"33","author":[{"given":"L.","family":"Misery","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital of Brest Brest France"},{"name":"Laboratory Interactions Neurons\u2010Keratinocytes (LINK) University of Western Brittany Brest France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1139-0908","authenticated-orcid":false,"given":"J.","family":"Seneschal","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pediatric Dermatology National Reference Centre for Rare Skin Disorders University Hospital of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Reguiai","sequence":"additional","affiliation":[{"name":"Courlancy Polyclinic Reims France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Merhand","sequence":"additional","affiliation":[{"name":"Association Fran\u00e7aise de l'Ecz\u00e9ma Redon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"H\u00e9as","sequence":"additional","affiliation":[{"name":"EA4636 University of Rennes 2 Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Huet","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital of Brest Brest France"},{"name":"Laboratory Interactions Neurons\u2010Keratinocytes (LINK) University of Western Brittany Brest France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Taieb","sequence":"additional","affiliation":[{"name":"European Market Maintenance Assessment Vincennes France"},{"name":"Department of Dermatology University Hospital of Necker Enfants Malades Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Ezzedine","sequence":"additional","affiliation":[{"name":"EA EpiDermE University Paris\u2010Est Paris France"},{"name":"Department of Dermatology University Hospital Henri Mondor Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,9,23]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"Education and Treatment in Human Sexuality: The Training of Health Professionals","author":"WHO","year":"1975"},{"key":"e_1_2_5_3_1","unstructured":"WHO.Defining sexual health. 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