{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:10:53Z","timestamp":1780733453050,"version":"3.54.1"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,11,15]],"date-time":"2018-11-15T00:00:00Z","timestamp":1542240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["104\u20102314\u2010B\u2010037\u2010048\u2010MY3"],"award-info":[{"award-number":["104\u20102314\u2010B\u2010037\u2010048\u2010MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH105\u20105R51"],"award-info":[{"award-number":["KMUH105\u20105R51"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH106\u20106R63"],"award-info":[{"award-number":["KMUH106\u20106R63"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Psoriasis is a common skin disease that has been recently found to be associated with various systemic inflammatory disorders. However, the association between psoriasis and gout has not been well defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>We investigated whether there is an association between psoriasis, psoriatic arthritis and gout in a large population of patients in Taiwan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A nationwide population\u2010based cross\u2010sectional study was performed using the Taiwanese National Health Insurance Research Database (<jats:styled-content style=\"fixed-case\">NHIRD<\/jats:styled-content>). A total of 114 623 patients with gout and 114 623 patients without gout (1 : 1 propensity score\u2010matched according to age, sex, income category and urbanization level) were identified. The prevalence of psoriasis, psoriatic arthritis and other comorbid diseases in these two groups of patients was compared. Adjusted odds ratios (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) were calculated using conditional logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was an increased prevalence of psoriasis in patients with gout compared with patients without gout (1.6% vs. 1.1%, <jats:italic>P<\/jats:italic> &lt; 0.0001). Subgroup analysis showed an increased prevalence of psoriatic arthritis (0.3% vs. 0.1%, <jats:italic>P<\/jats:italic> &lt; 0.0001) in patients with gout compared with patients without gout. In addition, multiple conditional logistic regression analysis showed that gout was significantly associated with psoriasis (adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.30, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.20\u20131.42) and psoriatic arthritis (adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.50, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.95\u20133.22). After stratification by age and sex, it was found that the strength of the association between gout and psoriasis was similar among males and females but varied according to age group, with patients aged 41\u201350 years having the strongest association.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Gout is significantly associated with psoriasis and psoriatic arthritis in the Taiwanese population, and the strength of the association varies with the patient's age. Further studies are warranted to elucidate the molecular mechanisms underlying this association.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.15290","type":"journal-article","created":{"date-parts":[[2018,10,14]],"date-time":"2018-10-14T10:10:58Z","timestamp":1539511858000},"page":"560-567","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Association between psoriasis, psoriatic arthritis and gout: a nationwide population\u2010based study"],"prefix":"10.1111","volume":"33","author":[{"given":"S.C.\u2010S.","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Dermatology College of Medicine Kaohsiung Medical University Kaohsiung Taiwan"},{"name":"Department of Dermatology Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Department of Medical Research Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Translational Research Center Kaohsiung Medical University Hospital 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