{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T01:39:35Z","timestamp":1787881175230,"version":"build-2784847793"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T00:00:00Z","timestamp":1547510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Though patient needs are key drivers of treatment decisions, they are rarely systematically investigated in routine care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed at analysing needs and expectations from the patient perspective in the German and Swiss psoriasis registries PsoBest and Swiss Dermatology Network of Targeted Therapies (SDNTT) with respect to treatment choice, age and gender.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The German and Swiss psoriasis registries observe patients recruited at first\u2010time use of systemic drugs. Within 10\u00a0years, clinical [Psoriasis Area Severity Index (<jats:styled-content style=\"fixed-case\">PASI<\/jats:styled-content>), Body Surface Area (<jats:styled-content style=\"fixed-case\">BSA<\/jats:styled-content>)] and patient\u2010reported outcomes are documented, including the Dermatology Quality of Life Index (<jats:styled-content style=\"fixed-case\">DLQI<\/jats:styled-content>) and the Patient Benefit Index (<jats:styled-content style=\"fixed-case\">PBI<\/jats:styled-content>), characterizing patient needs for treatment. The analysis data set includes <jats:italic>n<\/jats:italic>\u00a0=\u00a04894 patients from PsoBest and <jats:italic>n<\/jats:italic>\u00a0=\u00a0449 from <jats:styled-content style=\"fixed-case\">SDNTT<\/jats:styled-content> with mean follow\u2010up time of 7.5\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 5343 patients registered between 2008 and 2016 were included in the analyses (at baseline: 59.6% male, mean age 47.6\u00a0years\u00a0\u00b1\u00a014.5, <jats:styled-content style=\"fixed-case\">PASI<\/jats:styled-content> 14.2\u00a0\u00b1\u00a09.7, <jats:styled-content style=\"fixed-case\">BSA<\/jats:styled-content> 22.7\u00a0\u00b1\u00a019.7, <jats:styled-content style=\"fixed-case\">DLQI<\/jats:styled-content> 11.3\u00a0\u00b1\u00a07.2). The most important patient needs were to \u2018get better skin quickly\u2019 and to \u2018be healed of all skin defects\u2019.<\/jats:p><jats:p>Subgroup analyses by age revealed significant differences in needs, especially higher needs regarding social impairments in patients younger than 65\u00a0years. Patients 65\u00a0years or older attributed more importance to sleep quality, less dependency on medical visits, fewer side\u2010effects and confidence in the therapy. Out of 25 items reflecting patient needs, 20 items were rated significantly more important by women than men, with the greatest differences regarding feeling of depression, sleep quality and everyday productivity. Divided by treatment, needs were rated differently, recommending individualized and targeted choice of therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Age and gender stratify patient needs. Women showed higher expectations and rated specific needs in psoriasis treatment higher than men. Analysing the patient needs on an individual level will facilitate shared decisions by patient and physician in finding the optimal personalized treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.15324","type":"journal-article","created":{"date-parts":[[2018,11,2]],"date-time":"2018-11-02T18:23:49Z","timestamp":1541183029000},"page":"700-708","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":97,"title":["Gender and age significantly determine patient needs and treatment goals in psoriasis \u2013 a lesson for practice"],"prefix":"10.1111","volume":"33","author":[{"given":"J.\u2010T.","family":"Maul","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.A.","family":"Navarini","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Zurich Zurich 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