{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:43:50Z","timestamp":1790685830022,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,5]],"date-time":"2019-03-05T00:00:00Z","timestamp":1551744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Hidradenitis suppurativa (\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      ) is a chronic, relapsing, inflammatory skin disease characterized by painful inflamed nodules, recurrent abscesses and fistulas located in apocrine gland\u2013bearing body sites. The negative impact of\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      on patient's quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis and atopic eczema, and its improvement is an important goal in disease management. Nowadays, there are no specific validated QoL instruments available for\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      and generic dermatologic questionnaires are used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      The objective of this study was to demonstrate the validity, reliability and responsiveness of\n                      <jats:styled-content style=\"fixed-case\">HIDRA<\/jats:styled-content>\n                      disk, a new innovative tool designed for rapid assessment of\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      burden and, at the same time, an intuitive graphic visualization of the measurement outcome.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A multicentre, longitudinal, observational study was conducted to validate the\n                      <jats:styled-content style=\"fixed-case\">HIDRA<\/jats:styled-content>\n                      disk compared with other validated questionnaires [Skindex\u201016, Dermatology Life Quality Index (\n                      <jats:styled-content style=\"fixed-case\">DLQI<\/jats:styled-content>\n                      ), Work Productivity and Activity Impairment\u2013General Health (WPAI:GH)] and to evaluate its correlation with disease severity in Italian patients with any degree of\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      severity, as measured by Hurley stage and\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      Physician Global Assessment (\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">PGA<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 140 patients (59% women; mean age 34.9\u00a0\u00b1\u00a011.0\u00a0years) were enrolled in 27 dermatologic centres.\n                      <jats:styled-content style=\"fixed-case\">HIDRA<\/jats:styled-content>\n                      disk showed a strong correlation with Skindex\u201016 and\n                      <jats:styled-content style=\"fixed-case\">DLQI<\/jats:styled-content>\n                      , and a good one with WPAI:GH (correlation coefficient: 0.7568, 0.6651 and 0.5947, respectively) and a statistically significant correlation with both Hurley stage and\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">PGA<\/jats:styled-content>\n                      . Very good internal consistency (Cronbach coefficient &gt;0.80; intraclass correlation coefficient &gt;0.6), with correlation between the 10 items, good test\u2013retest reliability (Spearman correlation coefficient, 0.8331;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001) and responsiveness to changes were demonstrated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Our study shows that\n                      <jats:styled-content style=\"fixed-case\">HIDRA<\/jats:styled-content>\n                      disk, a short and innovative visual\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      QoL instrument, has been psychometrically validated in Italian language and it may help improve the management of\n                      <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>\n                      once implemented in routine clinical practice.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.15425","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T11:51:29Z","timestamp":1547207489000},"page":"766-773","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["HIDRAdisk: validation of an innovative visual tool to assess the burden of hidradenitis suppurativa"],"prefix":"10.1111","volume":"33","author":[{"given":"K.","family":"Peris","sequence":"first","affiliation":[{"name":"Istituto di Dermatologia Fondazione Policlinico Universitario A. 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