{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:46:26Z","timestamp":1790091986658,"version":"4.0.1"},"reference-count":189,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T00:00:00Z","timestamp":1552521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lasers and intense pulsed light sources (<jats:styled-content style=\"fixed-case\">IPLS<\/jats:styled-content>) are proposed for the treatment of many pigmentary disorders. They are sometimes considered as magic tools able to remove any type of lesions. Although being the best option for several hyperpigmented lesions, they can also worsen some conditions and have potential side\u2010effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this review was to give evidence\u2010based recommendations for the use of lasers and <jats:styled-content style=\"fixed-case\">IPLS<\/jats:styled-content> in the treatment of hyperpigmented lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>These recommendations were produced for the European Society of Laser Dermatology by a consensus panel made up of experts in the field of pigment laser surgery. Recommendations on the use of lasers and light treatments were made based on the quality of evidence for efficacy, safety, tolerability, cosmetic outcome, patient satisfaction\/preference and, where appropriate, on the experts' opinion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Lasers and <jats:styled-content style=\"fixed-case\">IPLS<\/jats:styled-content> are very effective for treating many hyperpigmented lesions such as lentigos, dermal hypermelanocytosis or heavy metal depositions. In the other hand, they have to be considered with great caution for other disorders, such as caf\u00e9 au lait macules, melasma or postinflammatory hyperpigmentation. After making the correct diagnosis, if lasers or <jats:styled-content style=\"fixed-case\">IPLS<\/jats:styled-content> are indicated, the optimal wavelengths and parameters will be chosen taking into account the skin phototype, origin and depth of the target pigments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although potentially very effective, lasers and <jats:styled-content style=\"fixed-case\">IPLS<\/jats:styled-content> cannot be proposed for all types of hyperpigmented lesions. In all cases, precise recognition of the disorder is mandatory for choosing between these devices and other therapeutic approaches.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.15497","type":"journal-article","created":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T04:12:22Z","timestamp":1552623142000},"page":"987-1005","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["Laser treatment of hyperpigmented lesions: position statement of the European Society of Laser in Dermatology"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0797-6570","authenticated-orcid":false,"given":"T.","family":"Passeron","sequence":"first","affiliation":[{"name":"Department of Dermatology Centre Hospitalier Universitaire Nice Universit\u00e9 C\u00f4t\u00e9 d'Azur Nice France"},{"name":"INSERM U1065, Team 12, C3M Universit\u00e9 C\u00f4t\u00e9 d'Azur Nice France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Genedy","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Department of Dermatology Alexandria University Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Salah","sequence":"additional","affiliation":[{"name":"Ministry of Health Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Fusade","sequence":"additional","affiliation":[{"name":"Laser Clinical Center Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Kositratna","sequence":"additional","affiliation":[{"name":"Department of Dermatology Massachusetts General Hospital Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010J.","family":"Laubach","sequence":"additional","affiliation":[{"name":"Department of Dermatology H\u00f4pitaux Universitaires de Gen\u00e8ve Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Marini","sequence":"additional","affiliation":[{"name":"The Skin Doctors Center Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Badawi","sequence":"additional","affiliation":[{"name":"National Institute of Laser Enhanced Sciences Cairo University Giza Egypt"},{"name":"Department of Dermatology Faculty of Medicine University of Szeged Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.274"},{"key":"e_1_2_6_3_1","volume-title":"Atlas of Pigmentary Disorders","author":"Passeron T","year":"2015"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6836297"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.34035.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12690"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2015.27.5.626"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70572-9"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.12.043"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12484"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.03050.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70449-6"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.01971.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.09.048"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03150.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.7.841"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000793"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34310.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04385.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2012.01426.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.01.012"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22514"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2011.560929"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2012.670707"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.1999.08171.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20246"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.00039.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002669900155"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000493"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/147641702321136246"},{"key":"e_1_2_6_31_1","first-page":"945","article-title":"Long\u2010pulse pulsed dye laser delivered with compression for treatment of facial lentigines","volume":"33","author":"Kono T","year":"2007","journal-title":"Dermatol Surg"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.34063.x"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2002.01175.x"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/146288300750163745"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.1999.tb00765.x"},{"key":"e_1_2_6_36_1","first-page":"109","article-title":"Common pigmentation disorders","volume":"79","author":"Plensdorf S","year":"2009","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910401)67:7<1990::AID-CNCR2820670728>3.0.CO;2-P"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.16.1701"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1195-328"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.21045"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2002.02103.x"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-014-1610-8"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.09243.x"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20603"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2016.1157358"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2010.07.002"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-006-0436-4"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199512000-00020"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.06.002"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.131.12.1416"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1996.d01-1103.x"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.119084"},{"key":"e_1_2_6_53_1","first-page":"5","article-title":"The use of lasers and intense pulsed light sources for the treatment of pigmentary lesions","volume":"9","author":"Chan HH","year":"2004","journal-title":"Skin Therapy Lett"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(88)70269-8"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1996.03890340027005"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.DSS.0000452635.06834.f5"},{"key":"e_1_2_6_57_1","first-page":"465","article-title":"Nevus spilus","volume":"80","author":"Vaidya DC","year":"2007","journal-title":"Cutis"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.11.941"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2000.00117-6.x"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1998.tb01342.x"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01261.x"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2009.08090"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1992.tb00615.x"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1996.tb01210.x"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1997.tb00227.x"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.1999.08192.x"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.01041.x"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1997.tb00062.x"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-2128-z"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.107650"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22443"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0123-y"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2012.01734.x"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2589"},{"key":"e_1_2_6_75_1","doi-asserted-by":"publisher","DOI":"10.1159\/000092286"},{"key":"e_1_2_6_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1998.tb04298.x"},{"key":"e_1_2_6_77_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246131"},{"key":"e_1_2_6_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01195.x"},{"key":"e_1_2_6_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-013-1314-5"},{"key":"e_1_2_6_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22465"},{"key":"e_1_2_6_81_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.12.1488"},{"key":"e_1_2_6_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06259.x"},{"key":"e_1_2_6_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.07.049"},{"key":"e_1_2_6_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70280-7"},{"key":"e_1_2_6_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)81505-8"},{"key":"e_1_2_6_86_1","first-page":"639","article-title":"Treatment of Ota's nevus by Q\u2010switched alexandrite laser : therapeutic outcome in relation to clinical and histopathological findings","volume":"9","author":"Kang W","year":"1999","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.21121"},{"key":"e_1_2_6_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22454"},{"key":"e_1_2_6_89_1","doi-asserted-by":"publisher","DOI":"10.5978\/islsm.16-OR-07"},{"key":"e_1_2_6_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12436"},{"key":"e_1_2_6_91_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.1997.tb00481.x"},{"key":"e_1_2_6_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)80313-8"},{"key":"e_1_2_6_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.10.054"},{"key":"e_1_2_6_94_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.01094.x"},{"key":"e_1_2_6_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2008.04061.x"},{"key":"e_1_2_6_96_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2009.21.3.255"},{"key":"e_1_2_6_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.05.043"},{"key":"e_1_2_6_98_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15301"},{"key":"e_1_2_6_99_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1700196"},{"key":"e_1_2_6_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2017.01.005"},{"key":"e_1_2_6_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2012.04.003"},{"key":"e_1_2_6_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.06.022"},{"key":"e_1_2_6_103_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000436852.32527.8a"},{"key":"e_1_2_6_104_1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1001\/archderm.1997.03890390089012","article-title":"Clinical and histological responses of congenital melanocytic nevi after single treatment with Q\u2010switched lasers","volume":"133","author":"Grevelink JM","year":"1997","journal-title":"Arch Dermatol"},{"key":"e_1_2_6_105_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000154866.01964.8c"},{"key":"e_1_2_6_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09153.x"},{"key":"e_1_2_6_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11058.x"},{"key":"e_1_2_6_108_1","first-page":"20","article-title":"Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color","volume":"3","author":"Davis EC","year":"2010","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_6_109_1","doi-asserted-by":"publisher","DOI":"10.2165\/11536930-000000000-00000"},{"key":"e_1_2_6_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1085-5629(97)80034-X"},{"key":"e_1_2_6_111_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12692"},{"key":"e_1_2_6_112_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2004.04019.x"},{"key":"e_1_2_6_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(03)00086-X"},{"key":"e_1_2_6_114_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2016.4399"},{"key":"e_1_2_6_115_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.99436"},{"key":"e_1_2_6_116_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.99268.x"},{"key":"e_1_2_6_117_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1994.tb00152.x"},{"key":"e_1_2_6_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03123.x"},{"key":"e_1_2_6_119_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2010.00527.x"},{"key":"e_1_2_6_120_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01643.x"},{"key":"e_1_2_6_121_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.172196"},{"key":"e_1_2_6_122_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01303.x"},{"key":"e_1_2_6_123_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01090.x"},{"key":"e_1_2_6_124_1","first-page":"42","article-title":"Refractory postinflammatory hyperpigmentation treated fractional CO2 laser","volume":"7","author":"Oram Y","year":"2014","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_6_125_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.10139"},{"key":"e_1_2_6_126_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000627"},{"key":"e_1_2_6_127_1","doi-asserted-by":"publisher","DOI":"10.4103\/2277-9175.186997"},{"key":"e_1_2_6_128_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12684"},{"key":"e_1_2_6_129_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12273"},{"key":"e_1_2_6_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.08.023"},{"key":"e_1_2_6_131_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.109"},{"key":"e_1_2_6_132_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12049"},{"key":"e_1_2_6_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.270"},{"key":"e_1_2_6_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.332"},{"key":"e_1_2_6_135_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08717.x"},{"key":"e_1_2_6_136_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2007.00288.x"},{"key":"e_1_2_6_137_1","first-page":"67","article-title":"Efficacy and safety of a new triple\u2010combination agent for the treatment of facial melasma","volume":"72","author":"Taylor SC","year":"2003","journal-title":"Cutis"},{"key":"e_1_2_6_138_1","first-page":"592","article-title":"A large 12\u2010month extension study of an 8\u2010week trial to evaluate the safety and efficacy of triple combination (TC) cream in melasma patients previously treated with TC cream or one of its dyads","volume":"4","author":"Torok H","year":"2005","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_6_139_1","first-page":"57","article-title":"Hydroquinone 4%, tretinoin 0.05%, fluocinolone acetonide 0.01%: a safe and efficacious 12\u2010month treatment for melasma","volume":"75","author":"Torok HM","year":"2005","journal-title":"Cutis"},{"key":"e_1_2_6_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2005.01.001"},{"key":"e_1_2_6_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.02.009"},{"key":"e_1_2_6_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.03.001"},{"key":"e_1_2_6_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.09.053"},{"key":"e_1_2_6_144_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01383.x"},{"key":"e_1_2_6_145_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20956"},{"key":"e_1_2_6_146_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.255"},{"key":"e_1_2_6_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.02.022"},{"key":"e_1_2_6_148_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000652"},{"key":"e_1_2_6_149_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34130.x"},{"key":"e_1_2_6_150_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-007-0803-4"},{"key":"e_1_2_6_151_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764170310021797"},{"key":"e_1_2_6_152_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12290"},{"key":"e_1_2_6_153_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30371.x"},{"key":"e_1_2_6_154_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.00315.x"},{"key":"e_1_2_6_155_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2012.01530.x"},{"key":"e_1_2_6_156_1","doi-asserted-by":"publisher","DOI":"10.2310\/6350.2005.31302"},{"key":"e_1_2_6_157_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764170510037752"},{"key":"e_1_2_6_158_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01264.x"},{"key":"e_1_2_6_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.01.048"},{"key":"e_1_2_6_160_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12176"},{"key":"e_1_2_6_161_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22100"},{"key":"e_1_2_6_162_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22518"},{"key":"e_1_2_6_163_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S147413"},{"key":"e_1_2_6_164_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22735"},{"key":"e_1_2_6_165_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/36.1.3"},{"key":"e_1_2_6_166_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13117"},{"key":"e_1_2_6_167_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01092.x"},{"key":"e_1_2_6_168_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.103036"},{"key":"e_1_2_6_169_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22463"},{"key":"e_1_2_6_170_1","first-page":"19","article-title":"Tetracycline treatment for sarcoid\u2010like ochronosis due to hydroquinone","volume":"42","author":"Fisher AA","year":"1988","journal-title":"Cutis"},{"key":"e_1_2_6_171_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0126-8"},{"key":"e_1_2_6_172_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1990.tb00326.x"},{"key":"e_1_2_6_173_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30177.x"},{"key":"e_1_2_6_174_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2012.758379"},{"key":"e_1_2_6_175_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2012.748198"},{"key":"e_1_2_6_176_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1992.tb03695.x"},{"key":"e_1_2_6_177_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1074"},{"key":"e_1_2_6_178_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.153"},{"key":"e_1_2_6_179_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12417"},{"key":"e_1_2_6_180_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22353"},{"key":"e_1_2_6_181_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34184.x"},{"key":"e_1_2_6_182_1","first-page":"385","article-title":"Dermatosis papulosa nigra","volume":"32","author":"Grimes PE","year":"1983","journal-title":"Cutis"},{"key":"e_1_2_6_183_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01358.x"},{"key":"e_1_2_6_184_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1983.tb02131.x"},{"key":"e_1_2_6_185_1","doi-asserted-by":"publisher","DOI":"10.1111\/1524-4725.2006.32000"},{"key":"e_1_2_6_186_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-1906-y"},{"key":"e_1_2_6_187_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01769.x"},{"key":"e_1_2_6_188_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764170801950070"},{"key":"e_1_2_6_189_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.EWX.0000464108.11136.ed"},{"key":"e_1_2_6_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0151-9638(18)30079-6"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.15497","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.15497","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.15497","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T08:12:13Z","timestamp":1694333533000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.15497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,14]]},"references-count":189,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1111\/jdv.15497"],"URL":"https:\/\/doi.org\/10.1111\/jdv.15497","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,14]]},"assertion":[{"value":"2018-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}