{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:17:53Z","timestamp":1790741873175,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T00:00:00Z","timestamp":1560729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hidradenitis suppurativa (HS) is a chronic debilitating skin disease, frequently located in the groin and anogenital area, leading to a substantial impact on quality of life and sexual health in patients with HS. Skin\u2010tissue\u2010sparing excision with electrosurgical peeling (STEEP) is a procedure with known low recurrence rates and high patient satisfaction in retrospective series. However, a prospective study to investigate the impact of any major surgery on specific aspects of the quality of life has not yet been performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess surgical outcomes and the effect of major surgery on the general quality of life, sexual health and activity impairment in patients with HS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A single centre prospective survey study was conducted among 40 patients undergoing major surgery. Surveys were completed prior to the surgery and 2, 6, 12 and 26\u00a0weeks after surgery. Besides the objective parameters (time to wound closure and surface of the wound), patient\u2010reported outcomes were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010nine patients with a total of 171 survey responses were included for analysis. Patients with Hurley stage I or II had a shorter time to wound closure (TTWC) compared to patients with Hurley stage III (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005). TTWC was significantly prolonged in patients treated with biologics (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Smoking did not significantly influence TTWC. For patient\u2010reported outcomes, DLQI and ASEX scores did not significantly improve during the study period of 6\u00a0months. However, activity and overall work impairment showed considerable improvement after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Time to wound closure is significantly prolonged by higher Hurley stage and treatment with biologics, contrastingly not by smoking. Major surgery improved the overall work and daily activity impairment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.15706","type":"journal-article","created":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T14:24:38Z","timestamp":1558967078000},"page":"1941-1946","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Surgical outcomes and the impact of major surgery on quality of life, activity impairment and sexual health in hidradenitis suppurativa patients: a prospective single centre study"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3751-684X","authenticated-orcid":false,"given":"L.M.","family":"Prens","sequence":"first","affiliation":[{"name":"Department of Dermatology, University Medical Center Groningen University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Huizinga","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Medical Center Groningen University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.C.","family":"Janse","sequence":"additional","affiliation":[{"name":"Department of Dermatology Meander Medical Center Amersfoort The Netherlands<!--Query ID=\"q3\" Text=\"AUTHOR: Please check that authors and their affiliations are correct.\"-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Medical Center Groningen University of Groningen Groningen The 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