{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:55:03Z","timestamp":1791284103009,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T00:00:00Z","timestamp":1566518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T00:00:00Z","timestamp":1566518400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Determining whether repigmentation within or adjacent to lentigo maligna or lentigo maligna melanoma (LM\/LMM) scars represents recurrence of melanoma is challenging. The use of reflectance confocal microscopy (RCM) and dermoscopy may aid in differentiating true melanoma recurrence from other causes of repigmentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe the characteristics of repigmentation within or adjacent to LM\/LMM scars observable on RCM and dermoscopy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analysed patients who presented with new pigmentation within or adjacent to scars from surgically treated LM\/LMM between January 2014 and December 2018. Clinical and demographic characteristics and time to recurrence were recorded. RCM was used to evaluate areas of pigmentation before biopsy. If available, dermoscopic images were also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 30 confocal studies in 29 patients were included in the study cohort. Twenty\u2010one patients had biopsy\u2010confirmed recurrent LM\/LMM; the remainder had pigmented actinic keratosis (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a04) or hyperpigmentation\/solar lentigo (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a05). RCM had sensitivity of 95.24% (95% CI, 76.18\u201399.88%), specificity of 77.7% (95% CI, 39.99\u201397.19%), positive predictive value of 90.91% (95% CI, 74.58\u201397.15%) and negative predictive value of 87.5% (95% CI, 50.04\u201398.0%). The most common dermoscopic feature observed among patients with recurrent LM\/LMM was focal homogeneous or structureless areas of light\u2010brown pigmentation (92.8% vs. 37.5% in patients with other diagnoses;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.009). LM\u2010specific dermoscopic criteria were present in only 28.5% of patients with recurrent LM\/LMM.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Reflectance confocal microscopy and dermoscopy are valuable tools for the comprehensive evaluation of repigmentation within or adjacent to LM scars.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.15819","type":"journal-article","created":{"date-parts":[[2019,7,20]],"date-time":"2019-07-20T14:19:27Z","timestamp":1563632367000},"page":"74-81","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Reflectance confocal microscopy and dermoscopy aid in evaluating repigmentation within or adjacent to lentigo maligna melanoma surgical scars"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4040-3640","authenticated-orcid":false,"given":"C.","family":"Navarrete\u2010Dechent","sequence":"first","affiliation":[{"name":"Dermatology Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA"},{"name":"Department of Dermatology, Escuela de Medicina Pontificia Universidad Catolica de Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Cordova","sequence":"additional","affiliation":[{"name":"Dermatology Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9566-8238","authenticated-orcid":false,"given":"K.","family":"Liopyris","sequence":"additional","affiliation":[{"name":"Dermatology Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0555-4822","authenticated-orcid":false,"given":"A.","family":"Rishpon","sequence":"additional","affiliation":[{"name":"Dermatology Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA"},{"name":"Department of Dermatology Tel Aviv Sourasky Medical Center Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Aleissa","sequence":"additional","affiliation":[{"name":"Dermatology Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Rossi","sequence":"additional","affiliation":[{"name":"Dermatology Service, Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA"},{"name":"Department of Dermatology Weill Cornell Medical College New York NY 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