{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T18:15:15Z","timestamp":1788372915603,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","issue":"S6","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hidradenitis suppurativa (<jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>) is a chronic, recurrent, inflammatory disease associated with a high physical and psychological burden. It is a disorder of the infundibular segment of the pilosebaceous unit, characterized by subcutaneous nodules, abscesses, sinus tracts and scar formation on the intertriginous and apocrine\u2010bearing areas. <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content> is quite rare in young and prepubertal children. It usually begins after puberty, but several reports of prepubertal <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content> onset have been described. These cases are strongly linked to hormonal disorders and genetic susceptibility. Specific guidelines for prepubertal patients are still lacking, so further studies are warranted to better delineate a tailored approach. This paper aims to summarize the most significant aspects, as well as the most recent information about the epidemiology, pathogenesis, clinical features, diagnosis, comorbidities and treatment of paediatric <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>. In addition, we report our clinical experience in managing <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content> in a group of eight prepubertal patients based on systemic antibiotics (azithromycin) and zinc oral supplementation.<\/jats:p>","DOI":"10.1111\/jdv.15827","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T10:07:22Z","timestamp":1568887642000},"page":"28-31","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Hidradenitis suppurativa in a prepubertal case series: a call for specific guidelines"],"prefix":"10.1111","volume":"33","author":[{"given":"A.","family":"Offidani","sequence":"first","affiliation":[{"name":"Dermatological Unit Department of Clinical and Molecular Sciences Polytechnic Marche University Ancona 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