{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:58:45Z","timestamp":1787187525361,"version":"build-2736575974"},"reference-count":7,"publisher":"Wiley","issue":"S6","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,10]]},"abstract":"Abstract<\/jats:title>Steatocystoma multiplex (SM<\/jats:styled-content>) is a rare autosomal dominant disease characterized by multiple asymptomatic intradermal true sebaceous cysts of variable size. These lesions may occasionally rupture, become inflamed, painful and heal with scarring [SM<\/jats:styled-content> suppurativa (SMS)], thus sharing overlapping features with hidradenitis suppurativa (HS<\/jats:styled-content>). The question of whether SMS<\/jats:styled-content> simply mimics HS<\/jats:styled-content> or if the two diseases may be associated remains open. We report three patients (2 M\/1 F; age: 47, 27 and 40\u00a0years) affected by SMS<\/jats:styled-content> showing inflammatory lesions on the areas typically affected by HS<\/jats:styled-content>. Repeated skin biopsy from each patient showed true sebaceous cysts in some specimens and findings compatible with HS<\/jats:styled-content>, without sebaceous glands evidence in others, supporting coexistence of the two diseases. Adalimumab at the initial dose of 160\u00a0mg (day 1), followed by 80\u00a0mg (day 15), and maintained at the dose of 40\u00a0mg every week from day 29 on, improved both HS<\/jats:styled-content> and SMS<\/jats:styled-content> lesions, including also non\u2010inflammatory cystic lesions.<\/jats:p>","DOI":"10.1111\/jdv.15848","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T10:07:22Z","timestamp":1568887642000},"page":"42-44","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Steatocystoma multiplex suppurativa associated with hidradenitis suppurativa successfully treated with adalimumab"],"prefix":"10.1111","volume":"33","author":[{"given":"L.","family":"Atzori","sequence":"first","affiliation":[{"name":"Section\u00a0of Dermatology Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Zanniello","sequence":"additional","affiliation":[{"name":"Section\u00a0of Dermatology Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Pilloni","sequence":"additional","affiliation":[{"name":"Section\u00a0of Pathology Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2227-581X","authenticated-orcid":false,"given":"F.","family":"Rongioletti","sequence":"additional","affiliation":[{"name":"Section\u00a0of Dermatology Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,19]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"892","article-title":"Numerous asymptomatic dermal cysts: Diagnosis and treatment of steatocystoma multiplex","volume":"64","author":"Georgakopoulos JR","year":"2018","journal-title":"Can Fam Physician"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20164539"},{"key":"e_1_2_4_4_1","first-page":"517","volume-title":"Weedon's Skin Pathology","author":"Patterson JW","year":"2016"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119424291.ch4"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03742.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1976.01630320038010"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2015.08.009"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.15848","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.15848","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.15848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T21:18:49Z","timestamp":1694294329000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.15848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,19]]},"references-count":7,"journal-issue":{"issue":"S6","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/jdv.15848"],"URL":"https:\/\/doi.org\/10.1111\/jdv.15848","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,19]]},"assertion":[{"value":"2019-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}