{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:27:17Z","timestamp":1791228437605,"version":"4.1.0"},"reference-count":6,"publisher":"Wiley","issue":"S6","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">SAPHO<\/jats:styled-content> syndrome, namely Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis, is a rare autoinflammatory chronic disease presenting with non\u2010infectious inflammatory osteitis, sterile joint inflammation and skin manifestations, including palmoplantar pustulosis and severe acne. The case of a 15\u2010year\u2010old boy affected by <jats:styled-content style=\"fixed-case\">SAPHO<\/jats:styled-content> syndrome and hidradenitis suppurativa (<jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>) is presented and discussed. Coexistence of these two diseases may represent a therapeutic challenge and this case confirms literature data reporting the efficacy of the combination of methotrexate and adalimumab in <jats:styled-content style=\"fixed-case\">SAPHO<\/jats:styled-content> complicated by <jats:styled-content style=\"fixed-case\">HS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/jdv.15849","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T10:07:22Z","timestamp":1568887642000},"page":"40-41","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Successful treatment of co\u2010existent <scp>SAPHO<\/scp> syndrome and hidradenitis suppurativa with adalimumab and methotrexate"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7636-958X","authenticated-orcid":false,"given":"G.","family":"Genovese","sequence":"first","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico Milan Italy"},{"name":"Department of Physiopathology and Transplantation Universit\u00e0 degli Studi di Milano Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Caorsi","sequence":"additional","affiliation":[{"name":"Centro per le malattie autoinfiammatorie ed immunodeficienze Clinica Pediatrica e Reumatologia IRCCS Istituto Giannina Gaslini Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Moltrasio","sequence":"additional","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8160-4169","authenticated-orcid":false,"given":"A.V.","family":"Marzano","sequence":"additional","affiliation":[{"name":"Dermatology Unit Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico Milan Italy"},{"name":"Department of Physiopathology and Transplantation Universit\u00e0 degli Studi di Milano Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,19]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-005-0199-5"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.130977"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.171007"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13740"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14691"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15226"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.15849","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.15849","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.15849","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T21:18:51Z","timestamp":1694294331000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.15849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,19]]},"references-count":6,"journal-issue":{"issue":"S6","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/jdv.15849"],"URL":"https:\/\/doi.org\/10.1111\/jdv.15849","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,19]]},"assertion":[{"value":"2019-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}