{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:21:15Z","timestamp":1791343275374,"version":"4.3.1"},"reference-count":187,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In addition to approved indications in non\u2010melanoma skin cancer in immunocompetent patients, topical photodynamic therapy (\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    ) has also been studied for its place in the treatment of, as well as its potential to prevent, superficial skin cancers in immune\u2010suppressed patients, although sustained clearance rates are lower than for immune\u2010competent individuals.\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    using a nanoemulsion of\n                    <jats:styled-content style=\"fixed-case\">ALA<\/jats:styled-content>\n                    in a daylight or conventional\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    protocol has been approved for use in field cancerization, although evidence of the potential of the treatment to prevent new\n                    <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>\n                    remained limited. High\u2010quality evidence supports a strong recommendation for the use of topical\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    in photorejuvenation as well as for acne, refractory warts, cutaneous leishmaniasis and in onychomycosis, although these indications currently lack approvals for use and protocols remain to be optimized, with more comparative evidence with established therapies required to establish its place in practice. Adverse events across all indications for\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    can be minimized through the use of modified and low\u2010irradiance regimens, with a low risk of contact allergy to photosensitizer prodrugs, and no other significant documented longer\u2010term risks with no current evidence of cumulative toxicity or photocarcinogenic risk. The literature on the pharmacoeconomics for using\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    is also reviewed, although accurate comparisons are difficult to establish in different healthcare settings, comparing hospital\/office\u2010based therapies of\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    and surgery with topical ointments, requiring inclusion of number of visits, real\u2010world efficacy as well as considering the value to be placed on cosmetic outcome and patient preference. This guideline, published over two parts, considers all current approved and emerging indications for the use of topical photodynamic therapy in Dermatology prepared by the\n                    <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                    subgroup of the European Dermatology Forum guidelines committee. It presents consensual expert recommendations reflecting current published evidence.\n                  <\/jats:p>","DOI":"10.1111\/jdv.16044","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T19:57:21Z","timestamp":1575575841000},"page":"17-29","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":143,"title":["European Dermatology Forum guidelines on topical photodynamic therapy 2019 Part 2: emerging indications \u2013 field cancerization, photorejuvenation and inflammatory\/infective dermatoses"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6035-0737","authenticated-orcid":false,"given":"C.A.","family":"Morton","sequence":"first","affiliation":[{"name":"Department of Dermatology Stirling Community Hospital Stirling UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8452-0737","authenticated-orcid":false,"given":"R.\u2010M.","family":"Szeimies","sequence":"additional","affiliation":[{"name":"Department of Dermatology Regensburg University Hospital Regensburg Germany"},{"name":"Department of Dermatology &amp; Allergology Klinikum Vest GmbH Recklinghausen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9136-1244","authenticated-orcid":false,"given":"N.","family":"Basset\u2010S\u00e9guin","sequence":"additional","affiliation":[{"name":"Department of Dermatology H\u00f4pital Saint Louis Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.G.","family":"Calzavara\u2010Pinton","sequence":"additional","affiliation":[{"name":"Department of Dermatology Spedali Civili Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Gilaberte","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario miguel servet IIS Arag\u00f3n Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"H\u00e6dersdal","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bispebjerg Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.F.L.","family":"Hofbauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Z\u00fcrich University Hospital Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.E.","family":"Hunger","sequence":"additional","affiliation":[{"name":"Department of Dermatology Inselspital Bern University Hospital University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Karrer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Regensburg University Hospital Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Piaserico","sequence":"additional","affiliation":[{"name":"Unit of Dermatology Department of Medicine University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ulrich","sequence":"additional","affiliation":[{"name":"Skin Cancer Centre Charit\u00e9 Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.\u2010M.","family":"Wennberg","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.R.","family":"Braathen","sequence":"additional","affiliation":[{"name":"Dermatology Bern Ittigen Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12031"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12026"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2015.2570"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17309"},{"key":"e_1_2_9_6_1","unstructured":"http:\/\/www.euroderm.org\/images\/stories\/guidelines\/guideline_Management_Actinic_Keratoses-update2011.pdf"},{"key":"e_1_2_9_7_1","unstructured":"http:\/\/www.euroderm.org\/images\/stories\/guidelines\/guideline_Basal_Cell_Carcinoma-update2012%20.pdf"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16017"},{"key":"e_1_2_9_9_1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.4414\/smw.2009.12725","article-title":"SGDV working group for organ transplant recipients. Swiss clinical practice guidelines for skin cancer in organ transplant recipients","volume":"139","author":"Hofbauer GF","year":"2009","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000107284.04969.5C"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.98075"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06054.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2007.05.040"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07616.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15884"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-003-0539-2"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2005.01949.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2011.04248.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09453.x"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550510042868"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318180731e"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700098"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01384.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13222"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195309)6:5<963::AID-CNCR2820060515>3.0.CO;2-Q"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12399372"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19960621)69:3<174::AID-IJC4>3.0.CO;2-X"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2014.154"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1159\/000254893"},{"key":"e_1_2_9_30_1","first-page":"18","article-title":"Defining field cancerization of the skin using noninvasive optical coherence tomography imaging to detect and monitor actinic keratosis in ingenol mebutate 0.015%\u2010 treated patients","volume":"9","author":"Markowitz O","year":"2016","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10887.x"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04356.x"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09492.x"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb03412.x"},{"key":"e_1_2_9_35_1","first-page":"827","article-title":"Photodynamic therapy as an alternative treatment for mycosis fungoides: a systematic review and meta\u2010analysis","volume":"153","author":"Seyed Jafari S","year":"2018","journal-title":"G It Derm Venereol"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155501750376276"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.00056.x"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)81742-2"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)91413-7"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2002.01119.x"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04245.x"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2006.00246.x"},{"key":"e_1_2_9_43_1","first-page":"785","article-title":"Plaque\u2010phase mycosis fungoides treated with photodynamic therapy: results in 12 patients","volume":"101","author":"Fernandez\u2010Guarino M","year":"2010","journal-title":"Actas Dermosifilogr"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1261"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.07.047"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2017.09.004"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2pp25125f"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.09.056"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00046.x"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06110.x"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04086.x"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.07107.x"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.12.033"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07340.x"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.09.057"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14345"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15495"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13191"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12312"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12413"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009366"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30053.x"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12059"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.1999.00441.x"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)90013-8"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546631003681078"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2009.00694.x"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02081.x"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2005.31011"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2005.23.202"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2009.00439.x"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2009.2566"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2003.05617.x"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12291"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.10048"},{"key":"e_1_2_9_76_1","first-page":"2925","article-title":"Photodynamic therapy of condyloma acuminata in pregnant women","volume":"125","author":"Yang YG","year":"2012","journal-title":"Chin Med J"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2003.05553.x"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06189.x"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07648.x"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2009.00467.x"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01125.x"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2018.07.014"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2018.06.022"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2006.02182.x"},{"key":"e_1_2_9_85_1","first-page":"CD005067","article-title":"Interventions for Old World cutaneous leishmaniasis","volume":"12","author":"Heras\u2010Mosteiro J","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.4.432"},{"key":"e_1_2_9_87_1","first-page":"902","article-title":"Photodynamic therapy as a new treatment of cutaneous leishmaniasis","volume":"12","author":"Ghaffarifar F","year":"2006","journal-title":"EastMediterr Health J"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2007.06177.x"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-004-0710-y"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2018.02.018"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02805.x"},{"key":"e_1_2_9_92_1","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1684\/ejd.2008.0587","article-title":"Successful treatment of cutaneous leishmaniasis by photodynamic therapy and cryotherapy","volume":"19","author":"Pizinger K","year":"2009","journal-title":"Eur J Dermatol"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13490"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2011.00610.x"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2007.00578.x"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061843"},{"key":"e_1_2_9_97_1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1610-0387.2012.08046.x","article-title":"Photodynamic therapy for skin rejuvenation: review and summary of the literature \u2013 results of a consensus conference of an expert group for aesthetic photodynamic therapy","volume":"11","author":"Karrer S","year":"2013","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2002.02018.x"},{"issue":"1","key":"e_1_2_9_99_1","first-page":"S36","article-title":"Effectiveness and safety of ALA\u2010IPL in treating actinic keratoses and photodamage","volume":"3","author":"Avram DK","year":"2004","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_100_1","first-page":"35","article-title":"Photorejuvenation of facial skin with topical 20% 5\u2010aminolevulinic acid and intense pulsed light treatment: a split\u2010face comparison study","volume":"4","author":"Alster TS","year":"2005","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.10.1247"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32163.x"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20781"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.00946.x"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2009.2733"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2011.590791"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01726.x"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14970"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07959.x"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20470"},{"key":"e_1_2_9_111_1","first-page":"633","article-title":"Photorejuvenation using topical 5\u2010methyl aminolevulinate and red light","volume":"7","author":"Ruiz\u2010Rodriguez R","year":"2008","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01385.x"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03687.x"},{"key":"e_1_2_9_114_1","first-page":"41","article-title":"The evolving role of aminolevulinic hydrochloride with photodynamic therapy in photoaging","volume":"69","author":"Gold MH","year":"2002","journal-title":"Cutis"},{"key":"e_1_2_9_115_1","first-page":"24","article-title":"PDT\/ALA in the treatment of actinic damage: real world experience","volume":"14","author":"Goldman MP","year":"2002","journal-title":"J Las Med Surg"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.1.33"},{"key":"e_1_2_9_117_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22323"},{"key":"e_1_2_9_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13327"},{"key":"e_1_2_9_119_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12233"},{"key":"e_1_2_9_120_1","first-page":"818","article-title":"Enhanced efficacy of photodynamic therapy after fractional resurfacing: fractional photodynamic rejuvenation","volume":"6","author":"Ruiz\u2010Rodriguez R","year":"2007","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_121_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17096"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1080\/147641700510037725"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.07.052"},{"key":"e_1_2_9_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.06.025"},{"key":"e_1_2_9_125_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2013.2050"},{"key":"e_1_2_9_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.25"},{"key":"e_1_2_9_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-016-1666-3"},{"key":"e_1_2_9_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201700357"},{"key":"e_1_2_9_129_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12658"},{"key":"e_1_2_9_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2016.02.005"},{"key":"e_1_2_9_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10270.x"},{"key":"e_1_2_9_132_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2007.17"},{"key":"e_1_2_9_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.06.015"},{"key":"e_1_2_9_134_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12042"},{"key":"e_1_2_9_135_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13842"},{"key":"e_1_2_9_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2017.06.010"},{"key":"e_1_2_9_137_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2874"},{"key":"e_1_2_9_138_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12420"},{"key":"e_1_2_9_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2016.07.010"},{"key":"e_1_2_9_140_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.9.1218"},{"key":"e_1_2_9_141_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20857"},{"key":"e_1_2_9_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-011-9434-6"},{"key":"e_1_2_9_143_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-014-9828-3"},{"key":"e_1_2_9_144_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2012.655258"},{"key":"e_1_2_9_145_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2013.3590"},{"key":"e_1_2_9_146_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14545"},{"key":"e_1_2_9_147_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2pp25124h"},{"key":"e_1_2_9_148_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01651.x"},{"key":"e_1_2_9_149_1","first-page":"501","article-title":"Photodynamic therapy with topical aminolevulinic acid and pulsed dye laser irradiation for sebaceous hyperplasia","volume":"2","author":"Alster TS","year":"2003","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_150_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10576.x"},{"key":"e_1_2_9_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2010.07.003"},{"key":"e_1_2_9_152_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-012-1295-4"},{"key":"e_1_2_9_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(98)00321-4"},{"key":"e_1_2_9_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.04.005"},{"key":"e_1_2_9_155_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02661.x"},{"key":"e_1_2_9_156_1","doi-asserted-by":"publisher","DOI":"10.1159\/000155643"},{"key":"e_1_2_9_157_1","doi-asserted-by":"publisher","DOI":"10.1159\/000182259"},{"key":"e_1_2_9_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2018.04.020"},{"key":"e_1_2_9_159_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2002.01164.x"},{"key":"e_1_2_9_160_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12097"},{"key":"e_1_2_9_161_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12319"},{"key":"e_1_2_9_162_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-11-13"},{"key":"e_1_2_9_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2014.11.004"},{"key":"e_1_2_9_164_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22142"},{"key":"e_1_2_9_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.04.008"},{"key":"e_1_2_9_166_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2012.757285"},{"key":"e_1_2_9_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2011.06.001"},{"key":"e_1_2_9_168_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22118"},{"key":"e_1_2_9_169_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2002.01065.x"},{"key":"e_1_2_9_170_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0098"},{"key":"e_1_2_9_171_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12301"},{"key":"e_1_2_9_172_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12051"},{"key":"e_1_2_9_173_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2013.02.002"},{"key":"e_1_2_9_174_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0392-0488.18.06011-X"},{"key":"e_1_2_9_175_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.02755.x"},{"key":"e_1_2_9_176_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.09024.x"},{"key":"e_1_2_9_177_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06211.x"},{"key":"e_1_2_9_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2017.07.002"},{"key":"e_1_2_9_179_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17131"},{"key":"e_1_2_9_180_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-018-0360-y"},{"key":"e_1_2_9_181_1","doi-asserted-by":"publisher","DOI":"10.2165\/11538670-000000000-00000"},{"key":"e_1_2_9_182_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-015-0211-7"},{"key":"e_1_2_9_183_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15269"},{"key":"e_1_2_9_184_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0392-0488.18.06071-6"},{"key":"e_1_2_9_185_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-016-0462-4"},{"key":"e_1_2_9_186_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2205"},{"key":"e_1_2_9_187_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03664.x"},{"key":"e_1_2_9_188_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13066"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.16044","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.16044","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.16044","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.16044","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:31:31Z","timestamp":1791282691000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.16044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,5]]},"references-count":187,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1111\/jdv.16044"],"URL":"https:\/\/doi.org\/10.1111\/jdv.16044","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,5]]},"assertion":[{"value":"2019-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}