{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:50:22Z","timestamp":1777438222400,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,1,19]],"date-time":"2020-01-19T00:00:00Z","timestamp":1579392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Metalworkers occupationally exposed to metals, tools, metalworking fluids (<jats:styled-content style=\"fixed-case\">MWF<\/jats:styled-content>s), technical oils, gloves, skin care products etc. frequently suffer from occupational dermatitis (<jats:styled-content style=\"fixed-case\">OD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate occupational exposure and to identify relevant occupational sensitizers in metalworkers with <jats:styled-content style=\"fixed-case\">OD<\/jats:styled-content>, and to evaluate suitability of current German patch test recommendations for this occupational group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>As part of the <jats:styled-content style=\"fixed-case\">OCCUDERM<\/jats:styled-content> project, occupational exposure of 230 metalworkers with suspected <jats:styled-content style=\"fixed-case\">OD<\/jats:styled-content> patch tested in the departments of dermatology in G\u00f6ttingen and Osnabr\u00fcck (both Lower Saxony, Germany) in 2012\u20132017 was recorded by questionnaire. These data, as well as results, of patch testing with standardized allergens and with workplace material were analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Metalworking fluids and skin care products were the most important exposures. Among <jats:styled-content style=\"fixed-case\">MWF<\/jats:styled-content> allergens, most frequently sensitizations to formaldehyde and formaldehyde releasers, colophony\/abietic acid and monoethanolamine were observed. Sensitization to methylisothiazolinone (<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content>) was frequent, probably as part of the general European epidemic of contact allergy to <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> in leave\u2010on cosmetics. Sensitization to glove ingredients only played a minor role.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The known occupational allergen spectrum could largely be confirmed. In order not to miss relevant sensitizations, patch testing with material from the patients\u2019 workplaces in parallel to baseline and <jats:styled-content style=\"fixed-case\">MWF<\/jats:styled-content> series is recommended. Sensitizations diagnosed could not always be linked to particular occupational exposures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.16130","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T13:55:30Z","timestamp":1575554130000},"page":"1536-1544","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Assessment of occupational exposure and spectrum of contact sensitization in metalworkers with occupational dermatitis: results of a cohort study within the <scp>OCCUDERM<\/scp> project"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2359-2518","authenticated-orcid":false,"given":"S.","family":"Schubert","sequence":"first","affiliation":[{"name":"Information Network of Departments of Dermatology (IVDK) Institute at the University Medical Center G\u00f6ttingen G\u00f6ttingen Germany"},{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Brans","sequence":"additional","affiliation":[{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"},{"name":"University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Reich","sequence":"additional","affiliation":[{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"},{"name":"Department of Dermatology, Venereology and Allergology University Medical Center G\u00f6ttingen G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"},{"name":"University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Buhl","sequence":"additional","affiliation":[{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"},{"name":"Department of Dermatology, Venereology and Allergology University Medical Center G\u00f6ttingen G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Skudlik","sequence":"additional","affiliation":[{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"},{"name":"University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mempel","sequence":"additional","affiliation":[{"name":"Hautarztpraxis Elmshorn Elmshorn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.P.","family":"Sch\u00f6n","sequence":"additional","affiliation":[{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"},{"name":"Department of Dermatology, Venereology and Allergology University Medical Center G\u00f6ttingen G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.M.","family":"John","sequence":"additional","affiliation":[{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"},{"name":"University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"Department of Dermatology, Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Geier","sequence":"additional","affiliation":[{"name":"Information Network of Departments of Dermatology (IVDK) Institute at the University Medical Center G\u00f6ttingen G\u00f6ttingen Germany"},{"name":"Lower\u2010Saxonian Institute of Occupational Dermatology Georg\u2010August University G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1989.tb03146.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2007.06039"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5414\/DBX00218"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajcd.2000.7186"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2003.480205.x"},{"key":"e_1_2_6_7_1","first-page":"232","article-title":"Vorschlag f\u00fcr die Epikutantestung bei Verdacht auf Kontaktallergie durch K\u00fchlschmierstoffe","volume":"48","author":"Geier J","year":"2000","journal-title":"Dermatol Beruf Umwelt"},{"key":"e_1_2_6_8_1","first-page":"141","article-title":"Kontaktsensibilisierungen bei Kfz\u2010 Mechanikern mit Berufsdermatose","volume":"62","author":"Cla\u00dfen A","year":"2014","journal-title":"Dermatol Beruf Umwelt"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000456"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13114"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2012.02834.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.5414\/DBP53107"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2004.00406.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2009.06787.x"},{"key":"e_1_2_6_15_1","unstructured":"(DKG) DKG.Arbeitsanweisung_Epikutantestung_pateigenes_Material 2019 [2019\u201010\u201024]. URLhttp:\/\/dkg.ivdk.org\/dok\/Arbeitsanweisung_Epikutantestung_pateigenes_Material_2019-02-20.pdf(last accessed: 05 September 2019)."},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-03827-3_57"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1710-1492-4-2-59"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-39684"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09085.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2000.043006327.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.5414\/DBX00342"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12123"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-004-0539-9"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2003.00187.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ffj.3247"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2002.470106.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13201"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12151"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-72451-5_36-1"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01194.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12952"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2010.01863.x"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.16130","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.16130","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.16130","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.16130","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T18:29:39Z","timestamp":1693938579000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.16130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,19]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/jdv.16130"],"URL":"https:\/\/doi.org\/10.1111\/jdv.16130","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,19]]},"assertion":[{"value":"2019-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}