{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:33:45Z","timestamp":1780472025287,"version":"3.54.1"},"reference-count":43,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T00:00:00Z","timestamp":1590624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Data regarding the course and treatment of pigmented purpuric dermatoses (PPD) in the paediatric population are limited. Although treatments for pigmented purpura are not well established, vitamin C and rutoside have been reported to be an effective treatment option and are widely utilized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the clinical course and utility of vitamin C and rutoside in paediatric patients with PPD treated at Ann &amp; Robert H. Lurie Children\u2019s Hospital of Chicago between 2008 and 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of all children with PPD managed at our hospital between 2008 and 2018 was performed. Additional follow\u2010up was obtained via telephone interviews.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 101 patients met inclusion criteria. The female: male ratio was 1.3\u00a0:\u00a01, and the median age at diagnosis was 8.8\u00a0years (IQR, 5.7\u201312.9). Median follow\u2010up was 7.13\u00a0months (IQR, 3\u201317.4). The most common PPD subtypes were lichen aureus (43%) and Schamberg (34%). Fifty\u2010three (52%) patients had evaluable follow\u2010up documentation via their medical record or phone questionnaire. Twenty\u2010eight patients were treated with vitamin C or rutoside or combination therapy. Twenty\u2010five patients received no treatment. Clearance of the rash was noted in 24 (45.3%) patients overall, including 10 (42%) patients in the treated group and 14 (58%) patients in the untreated group. Recurrence was noted in seven (13.2%) patients. Treatment with vitamin C and\/or rutoside was well tolerated without side effects. None of the patients were subsequently diagnosed with vasculitis, coagulopathy or cutaneous T\u2010cell lymphoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pigmented purpuric dermatosis in children is a benign disorder with high rates of complete resolution. Treatment with vitamin C and rutoside is well tolerated, but in this cohort, there did not appear to be an advantage over watchful waiting without therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.16397","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T07:07:16Z","timestamp":1585724836000},"page":"2402-2408","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Pigmented purpuric dermatosis in children: a retrospective cohort with emphasis on treatment and outcomes"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0967-3968","authenticated-orcid":false,"given":"A.","family":"Ollech","sequence":"first","affiliation":[{"name":"Division of Dermatology Ann &amp; Robert H. 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