{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:41:04Z","timestamp":1790620864498,"version":"4.1.0"},"reference-count":57,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Ministry of Innovation and Technology in Hungary","award":["NKFIH-1163-10\/2019"],"award-info":[{"award-number":["NKFIH-1163-10\/2019"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Numerous generic, skin\u2010 and disease\u2010specific health\u2010related quality of life (HRQoL) measures are available for patients with hidradenitis suppurativa (HS). Yet, robust psychometric evidence is lacking in many aspects of these outcome measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We sought to determine convergent and known\u2010groups validity of multiple generic and skin\u2010specific HRQoL measures and to identify predictors of impaired HRQoL in patients with HS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2017 and 2019, a multicentre cross\u2010sectional study was carried out involving 200 consecutive HS patients. HRQoL outcomes included the EQ\u20105D\u20105L, EQ visual analogue scale (EQ VAS), Skindex\u201016, Dermatology Life Quality Index (DLQI) and DLQI\u2010Relevant (DLQI\u2010R). Disease severity was graded by HS\u2010Physician\u2019s Global Assessment (HS\u2010PGA) scale and the Modified Sartorius scale (MSS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 77%, 56%, 51%, 46% and 28% reported problems in the pain\/discomfort, usual activities, anxiety\/depression, mobility and self\u2010care dimensions of EQ\u20105D\u20105L. Mean \u00b1 SD EQ VAS, DLQI and DLQI\u2010R  scores were 64.29 \u00b1 22.68, 11.75 \u00b1 8.11 and 12.19 \u00b1 8.33, respectively. Skindex\u201016 responses indicated that the emotional burden of HS (64.55 \u00b1 29.28) far exceeded those of functioning (49.40 \u00b1 34.70) and physical symptoms (46.74 \u00b1 29.36). EQ\u20105D\u20105L, EQ VAS, DLQI, DLQI\u2010R and Skindex\u201016 total scores had moderate or strong correlations with each other (range: |0.487| to |0.993|), weak or moderate correlations with HS\u2010PGA (|0.350| to |0.433|) and weak correlations with MSS (|0.324| to |0.389|). DLQI\u2010R slightly outperformed DLQI both in terms of convergent and known\u2010groups validity. Being female, lower education level, more severe disease and genital involvement were associated with worse HRQoL (P &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study provides high\u2010quality evidence that among skin\u2010specific outcomes, the DLQI, DLQI\u2010R and Skindex\u201016, and among generic instruments, the EQ\u20105D\u20105L are suitable to be used in HS patients. In future research, we recommend the use of existing well\u2010validated HRQoL tools instead of developing new measures for each study. The development of composite measures that combine physician\u2010 and patient\u2010reported outcomes is not supported by evidence in HS.<\/jats:p><jats:p>[Correction added on 25 July 2020, after first online publication: in the Abstract section, the \u00b1 signs were missing and have been added to this version.]<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.16642","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T06:01:23Z","timestamp":1593756083000},"page":"2584-2592","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Validity of EQ\u20105D\u20105L, Skindex\u201016, DLQI and DLQI\u2010R in patients with hidradenitis suppurativa"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5266-4667","authenticated-orcid":false,"given":"L.H.","family":"Gergely","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Dermatooncology Faculty of Medicine Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6530-7052","authenticated-orcid":false,"given":"K.","family":"G\u00e1sp\u00e1r","sequence":"additional","affiliation":[{"name":"Departments of Dermatology Faculty of Medicine University of Debrecen Debrecen Hungary"},{"name":"Department of Dermatological Allergology Faculty of Medicine University of Debrecen Debrecen Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6095-2295","authenticated-orcid":false,"given":"V.","family":"Brodszky","sequence":"additional","affiliation":[{"name":"Department of Health Economics Corvinus University of Budapest Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1.","family":"Kiny\u00f3","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Oncodermatology University of P\u00e9cs Medical School P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2109-9014","authenticated-orcid":false,"given":"A.","family":"Szegedi","sequence":"additional","affiliation":[{"name":"Departments of Dermatology Faculty of Medicine University of Debrecen Debrecen Hungary"},{"name":"Department of Dermatological Allergology Faculty of Medicine University of Debrecen Debrecen Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0973-5228","authenticated-orcid":false,"given":"\u00c9.","family":"Remenyik","sequence":"additional","affiliation":[{"name":"Departments of Dermatology Faculty of Medicine University of Debrecen Debrecen Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9947-1755","authenticated-orcid":false,"given":"N.F.","family":"Kiss","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Dermatooncology Faculty of Medicine Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1450-4790","authenticated-orcid":false,"given":"A.","family":"Bat\u00f3","sequence":"additional","affiliation":[{"name":"Department of Health Economics Corvinus University of Budapest Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9636-6012","authenticated-orcid":false,"given":"M.","family":"P\u00e9ntek","sequence":"additional","affiliation":[{"name":"Department of Health Economics Corvinus University of Budapest Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9285-8746","authenticated-orcid":false,"given":"L.","family":"Gul\u00e1csi","sequence":"additional","affiliation":[{"name":"Department of Health Economics Corvinus University of Budapest Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4306-5093","authenticated-orcid":false,"given":"M.","family":"S\u00e1rdy","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Dermatooncology Faculty of Medicine Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7071-1364","authenticated-orcid":false,"given":"A.","family":"B\u00e1nv\u00f6lgyi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Dermatooncology Faculty of Medicine Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4949-8711","authenticated-orcid":false,"given":"N.","family":"Wikonk\u00e1l","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Dermatooncology Faculty of Medicine Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9674-620X","authenticated-orcid":false,"given":"F.","family":"Rencz","sequence":"additional","affiliation":[{"name":"Department of Health Economics Corvinus University of Budapest Budapest Hungary"},{"name":"Premium Postdoctoral Research Programme Hungarian Academy of Sciences Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.02.067"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.16691"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12966"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15940"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.06.020"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90321-7"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.08.090"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.0201"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/postgradmedj-2013-131994"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15519"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16672"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16603"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18692"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475416677721"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.08.030"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15122"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14475"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14418"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16927"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/120347540100500202"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18435"},{"key":"e_1_2_6_23_1","first-page":"1167","article-title":"Dermatology Life Quality Index (DLQI) score bands are applicable to DLQI\u2010Relevant (DLQI\u2010R) scoring","volume":"182","author":"Rencz F","year":"2020","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18142"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15425"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-014-0638-9"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18451"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-017-1699-x"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16883"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8510(90)90421-9"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9903-x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.07.027"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2129"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000358009"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0866"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14511"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-016-1375-6"},{"key":"e_1_2_6_38_1","article-title":"Parallel valuation of the EQ\u20105D\u20103L and EQ\u20105D\u20105L in Hungary","author":"Rencz F","year":"2020","journal-title":"Value Health"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01167.x"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-157-12-201212180-00004"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09198.x"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2006.03.012"},{"key":"e_1_2_6_43_1","article-title":"Factors affecting quality of life in patients with hidradenitis suppurativa","author":"Jorgensen AR","year":"2019","journal-title":"Arch Dermatol Res"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04468.x"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.061"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-014-0105-5"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1159\/000475822"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17508"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1159\/000455236"},{"key":"e_1_2_6_50_1","volume-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen J","year":"1988"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14686"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15748"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.05.040"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15255"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15537"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14676"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.5655"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2019.4659"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.16642","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.16642","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.16642","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.16642","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T19:47:18Z","timestamp":1693770438000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.16642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,2]]},"references-count":57,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/jdv.16642"],"URL":"https:\/\/doi.org\/10.1111\/jdv.16642","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,2]]},"assertion":[{"value":"2020-02-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}