{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:09:16Z","timestamp":1787015356035,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Research and Quality","doi-asserted-by":"publisher","award":["K12 HS023011"],"award-info":[{"award-number":["K12 HS023011"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001582","name":"Dermatology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001582","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009754","name":"Galderma","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009754","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR000150"],"award-info":[{"award-number":["UL1TR000150"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Multiple clinician\u2010reported outcome measures exist for atopic dermatitis (AD) severity. However, there is no gold standard for use in clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the measurement properties of the product of validated Investigator's Global Assessment for AD (vIGA) and body surface area (BSA) overall or divided into six categories (cBSA: 0%\/0.1, &lt;10%\/10, &lt;30%\/30, &lt;50%\/50, &lt;70%\/70 and &lt;90%\/90\u2013100%) and compare with other clinician\u2010reported and patient\u2010reported outcomes in adults and children with AD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We performed a prospective dermatology practice\u2010based study using questionnaires and evaluation by a dermatologist (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0653).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>vIGA*BSA and vIGA*cBSA had good convergent validity with BSA (Spearman's \u03c1\u00a0=\u00a00.97 and 0.93), eczema area and severity index (\u03c1\u00a0=\u00a00.94 and 0.92), and objective SCORAD (\u03c1\u00a0=\u00a00.88 and 0.89); and weak\u2010to\u2010good convergent validity with Numeric Rating Scale average itch (\u03c1\u00a0=\u00a00.22 and 0.22) and worst itch (\u03c1\u00a0=\u00a00.27 and 0.28), Patient\u2010Oriented Eczema Measure (\u03c1\u00a0=\u00a00.44 and 0.43), Dermatology Life Quality Index (\u03c1\u00a0=\u00a00.48 and 0.49), ItchyQOL (\u03c1\u00a0=\u00a00.45 and 0.46), PROMIS Sleep Disturbance (\u03c1\u00a0=\u00a00.46 and 0.37) and sleep\u2010related impairment (\u03c1\u00a0=\u00a00.31 and 0.31) in adults and\/or children; very good discriminant validity for physician\u2010reported global AD severity; good responsiveness to change of severity of AD and itch; and good reliability (intraclass correlation coefficient [95% confidence interval]: 0.72 [0.60\u20130.81] and 0.74 [0.62\u20130.82]) with no floor or ceiling effects. Thresholds for interpretability bands and clinically important difference were established.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>vIGA*BSA and vIGA*cBSA scores showed good convergent and discriminant validity, reliability, responsiveness and interpretability in adults and children with AD, and were feasible for use in clinical practice. vIGA*BSA and vIGA*cBSA had slightly lower convergent validity than EASI or objective SCORAD, but might be more efficient to collect and score.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.16846","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T17:13:37Z","timestamp":1596474817000},"page":"180-187","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Measurement properties of the product of investigator\u2019s global assessment and body surface area in children and adults with atopic dermatitis"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3686-7805","authenticated-orcid":false,"given":"J.I.","family":"Silverberg","sequence":"first","affiliation":[{"name":"Department of Dermatology The George Washington University School of Medicine and Health Sciences Washington DC USA"},{"name":"Department of Dermatology Feinberg School of Medicine Northwestern University Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6408-5512","authenticated-orcid":false,"given":"D.","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Dermatology Feinberg School of Medicine Northwestern University Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3458-4484","authenticated-orcid":false,"given":"M.","family":"Yousaf","sequence":"additional","affiliation":[{"name":"Department of Dermatology Feinberg School of Medicine Northwestern University Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8700-480X","authenticated-orcid":false,"given":"S.R.","family":"Janmohamed","sequence":"additional","affiliation":[{"name":"Department of Dermatology Feinberg School of Medicine Northwestern University Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7945-0981","authenticated-orcid":false,"given":"P.P.","family":"Vakharia","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Texas Southwestern Medical Center Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8150-6358","authenticated-orcid":false,"given":"R.","family":"Chopra","sequence":"additional","affiliation":[{"name":"State University of New York Downstate Medical Center Brooklyn NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1959-1563","authenticated-orcid":false,"given":"R.","family":"Chavda","sequence":"additional","affiliation":[{"name":"Galderma SA Rx Strategy &amp; 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