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These studies also help to complement data reported in clinical studies. Fixed\u2010dose combination calcipotriol 50\u00a0\u00b5g\/g plus betamethasone dipropionate 0.5\u00a0mg\/g cutaneous foam (Cal\/BD foam) is a topical agent used for the treatment of psoriasis vulgaris. In clinical studies, Cal\/BD foam has demonstrated a significantly greater efficacy and rapid onset of action compared with both single and combination formulations such as ointments and gels. To date, three observational studies have examined the real\u2010world efficacy and safety of Cal\/BD foam in clinical practice in the United States, Germany and Spain. Data gathered from these studies reinforce the positive findings reported in clinical studies assessing Cal\/BD foam for the treatment of psoriasis and demonstrate improved patient satisfaction with Cal\/BD foam. Using Cal\/BD foam has been shown to be cost\u2010effective based on results from randomised clinical trials and cost\u2010effective analysis. As such, Cal\/BD foam has the potential to lower treatment costs by reducing the need for some patients to progress to more expensive treatments, such as phototherapy and biologics. Cal\/BD foam is therefore a cost\u2010effective solution for the treatment of psoriasis vulgaris that should be considered when prescribing topicals.<\/jats:p>","DOI":"10.1111\/jdv.17084","type":"journal-article","created":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T08:02:48Z","timestamp":1614067368000},"page":"28-34","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Calcipotriol\/betamethasone dipropionate foam demonstrates comparable efficacy to clinical trial data in the real world, improves patient satisfaction and is cost\u2010effective"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0064-8707","authenticated-orcid":false,"given":"A.","family":"Armstrong","sequence":"first","affiliation":[{"name":"University of Southern California Los Angeles CA 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