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Incidences of these diseases vary considerably between different populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To establish a registry prospectively recruiting all AIBD patients in a geographically well\u2010defined region in Northern Germany (Schleswig\u2010Holstein).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Only patients with verified disease (by clinical presentation, histology, direct and\/or indirect immunofluorescence and \/or ELISA) living in Schleswig\u2010Holstein were included. Incidences of PD were estimated based on the total number of inhabitants in Schleswig\u2010Holstein, stratified by birth year and sex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 67 patients with PD [35 male, 32 female, mean age 75 (standard deviation 14.3\u00a0years)], 83% were patients with bullous pemphigoid [<jats:italic>n<\/jats:italic>\u00a0=\u00a056, 28 male, 28 female, mean age 78 (SD 9.9)]. The resulting crude incidences were 23.4 patients\/million\/year for all pemphigoid patients, 19.6 patients\/million\/year for bullous pemphigoid (age\u2010standardized 16.9 patients\/million\/year) with a strong increase in bullous pemphigoid patients in the age group of 85\u201390\u00a0years with 262 patients\/million\/year. Incidences for bullous pemphigoid were higher in urban compared to rural areas. Other PD (mucous membrane pemphigoid, linear IgA disease, anti\u2010p200 pemphigoid) were less frequent with crude incidences of 2.1, 1.0 and 0.7 patients\/million\/year, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study prospectively analyses the incidence of PD in a carefully defined geographical area. The highest incidence among PD patients was found for bullous pemphigoid. The incidence of bullous pemphigoid is considerably increased compared to previous reports and reveals regional differences. Further studies are needed in order to clarify these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.17107","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T06:13:33Z","timestamp":1610691213000},"page":"1197-1202","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Incidence of pemphigoid diseases in Northern Germany in 2016 \u2013 first data from the Schleswig\u2010Holstein Registry of Autoimmune Bullous Diseases"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3265-0011","authenticated-orcid":false,"given":"N.","family":"van Beek","sequence":"first","affiliation":[{"name":"Department of Dermatology, Allergology, and Venereology University of L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Weidinger","sequence":"additional","affiliation":[{"name":"Department of Dermatology, 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