{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T19:07:46Z","timestamp":1780772866017,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T00:00:00Z","timestamp":1621123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In the era of precision medicine, identification of possible predictive factors of clinical response to treatment is fundamental. This need is particularly strong for anogenital warts (AGW), because there are several treatment modalities with different clearance and recurrence rates. However, data regarding the effect of mental health parameters on response to treatment in patients with AGW are lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of the present study was to evaluate the association between patients\u2019 mental health parameters and AGW treatment outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010centre, prospective study that included newly diagnosed male patients with AGW. At their initial visit, all patients completed the State\u2010Trait Anxiety Inventory (STAI), the Symptom Checklist\u201090\u2010Revised (SCL\u201090\u2010R) and the Eysenck Personality Questionnaire (EPQ) questionnaires, which evaluate anxiety, psychopathological manifestations and personality traits, respectively. All patients received cryotherapy until clearance of lesions and were followed up for 18\u00a0months for detection of recurrences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 167 male patients. The mean number of days for AGW clearance was 89\u00a0\u00b1\u00a065. During the 18\u2010month follow\u2010up, 28% of participants showed a recurrence, after a mean number of 150\u00a0\u00b1\u00a0132\u00a0days. No statistically significant association was detected between questionnaires scores and (a) time needed for AGW clearance, (b) time until 1st recurrence and (c) number of recurrences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>If confirmed, our findings indicate that we may not need to modify our AGW treatment plan according to a patient\u2019s mental health profile.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.17324","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T16:59:01Z","timestamp":1619715541000},"page":"1859-1864","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The effect of anxiety, psychopathological symptoms and personality traits on response to treatment in male patients with anogenital warts: a prospective study"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0066-212X","authenticated-orcid":false,"given":"G.","family":"Tyros","sequence":"first","affiliation":[{"name":"1st Department of Dermatology and Venereology Medical School National and Kapodistrian University of Athens \u201cA. 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Sygros\u201d Hospital for Skin and Venereal Diseases Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tagka","sequence":"additional","affiliation":[{"name":"1st Department of Dermatology and Venereology Medical School National and Kapodistrian University of Athens \u201cA. Sygros\u201d Hospital for Skin and Venereal Diseases Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Stratigos","sequence":"additional","affiliation":[{"name":"1st Department of Dermatology and Venereology Medical School National and Kapodistrian University of Athens \u201cA. Sygros\u201d Hospital for Skin and Venereal Diseases Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8221-0217","authenticated-orcid":false,"given":"E.","family":"Nicolaidou","sequence":"additional","affiliation":[{"name":"1st Department of Dermatology and Venereology Medical School National and Kapodistrian University of Athens \u201cA. 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