{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:29:30Z","timestamp":1790504970886,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T00:00:00Z","timestamp":1636675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vitiligo management is challenging and requires long\u2010term adherence of patients who often complain of the burden associated with treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To develop and validate a patient reported measurement of the burden of treatment in vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was nested within the ComPaRe Vitiligo e\u2010cohort, an online e\u2010cohort of vitiligo patients in France. Items were derived from a literature review and from the qualitative analysis of a survey using open\u2010ended questions of 204 patients with Vitiligo. Construct validity of the resulting instrument was assessed by comparing the instrument's score to the Dermatology Life Quality Index (DLQI), Vitiligo Impact Patient score (VIPs) and Treatment Burden Questionnaire (TBQ) scores. Reliability was assessed by test\u2010retest with 15\u2009\u00b1\u200910\u2009days of interval between both assessments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 343 adult participants participated in the validation of the Vitiligo Treatment Impact score (VITs). The VITs is a 19\u2010item questionnaire assessing the burden of treatment in patients with vitiligo with results suggesting four domains (\u2018Finding a doctor\u2019, \u2018Phototherapy\u2019, \u2018Topical treatment\u2019 and \u2018Impact on outdoor activities and photoprotection\u2019). The VITs total score was well correlated with the DLQI, VIP and TBQ scores. Agreement between test and retest was good (ICC 0.705, 95% CI 0.491\u20130.818).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We developed a patient reported measurement of the burden of treatment in vitiligo with good psychometric properties.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.17742","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T21:24:30Z","timestamp":1634678670000},"page":"279-285","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Vitiligo Treatment Impact score (VITs): development and validation of a vitiligo burden of treatment questionnaire using the ComPaRe Vitiligo e\u2010cohort"],"prefix":"10.1111","volume":"36","author":[{"given":"J.","family":"Shourick","sequence":"first","affiliation":[{"name":"Service de Dermatologie AP\u2010HP H\u00f4pital Henri\u2010Mondor Cr\u00e9teil France"},{"name":"EpiDermE \u2010 Epidemiology in Dermatology and Evaluation of Therapeutics Universit\u00e9 Paris\u2010Est Cr\u00e9teil Creteil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1139-0908","authenticated-orcid":false,"given":"J.","family":"Seneschal","sequence":"additional","affiliation":[{"name":"Service de Dermatologie Centre de R\u00e9f\u00e9rence des Maladies Rares de la Peau H\u00f4pital Saint Andr\u00e9 CHU de Bordeaux Bordeaux France"},{"name":"INSERM BMGIC U1035 Univ. 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