{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T13:49:08Z","timestamp":1783950548508,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T00:00:00Z","timestamp":1637020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Occupational hand eczema is common among hairdressers and implementing effective preventive measures requires a good understanding of the disease\u2019s epidemiology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the long\u2010term development of hand eczema (HE) in hairdressers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort study of all hairdressers graduating from Danish hairdressing vocational schools from 1985 to 2007 was conducted. A self\u2010administered questionnaire was sent in 2009 with follow\u2010up in 2020. Data from the Danish labour market supplementary pension scheme provided information on yearly affiliation with the hairdressing trade.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cumulative lifetime prevalence of HE increased from 42.3% at baseline to 45.2% at follow\u2010up (odds ratio [OR], 1.1; 95% confidence interval [CI], 1.0\u20101.2). The incidence rate decreased from 42.8 cases\/1000 person\u2010years (95% CI, 40.8\u201344.8) at baseline to 3.4 cases\/1000 person\u2010years (95% CI, 2.5\u20134.6) within the follow\u2010up period. HE onset occurred within 8\u2009years of beginning an apprenticeship for &gt;90% of cases and occurred within the apprenticeship period for 68% of cases. The risk factors associated with having had HE at baseline were a previous positive patch test (adjusted OR [aOR], 5.3; 95% CI, 4.2\u20136.6), a history of atopic dermatitis (aOR, 3.4; 95% CI, 2.9\u20134.0) and female sex (aOR, 1.8; 95% CI 1.4\u20132.3). The most important risk factors at follow\u2010up were previous HE (aOR, 10.1; 95% CI, 7.3\u201313.8) and a positive patch test within the follow\u2010up period (aOR, 4.5; 95% CI, 3.0\u20136.8). Among the hairdressers who had HE at baseline, 65.5% exhibited remission, whereas 34.6% had persistent and often severe HE at follow\u2010up. Hairdressers with persistent HE were the subgroup of the study population most frequently affected by the risk factors identified for HE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Primary prevention of HE should focus on hairdressing apprentices and fully trained hairdressers who have recently graduated. Approximately one\u2010third of trained hairdressers develop persistent and often severe HE, emphasizing the need for early intervention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.17794","type":"journal-article","created":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T12:14:00Z","timestamp":1636373640000},"page":"263-270","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Long\u2010term follow\u2010up of hand eczema in hairdressers: a prospective cohort study of Danish hairdressers graduating from 1985 to 2007"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2147-016X","authenticated-orcid":false,"given":"M.","family":"Havmose","sequence":"first","affiliation":[{"name":"National Allergy Research Center Department of Dermatology and Allergy Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3770-1743","authenticated-orcid":false,"given":"J.P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"National Allergy Research Center Department of Dermatology and Allergy Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Zachariae","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine University of Copenhagen Copenhagen Denmark"},{"name":"Department of Dermatology and Allergy Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.D.","family":"Johansen","sequence":"additional","affiliation":[{"name":"National Allergy Research Center Department of Dermatology and Allergy Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen Copenhagen Denmark"},{"name":"Department of Dermatology and Allergy Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12045"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000342175"},{"key":"e_1_2_9_4_1","unstructured":"Reported work related injuries in Denmark 2019Work Environment in Denmark. 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