{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:43:52Z","timestamp":1790685832308,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T00:00:00Z","timestamp":1640217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>A large discrepancy between physician\u2010diagnosed and self\u2010reported Hidradenitis suppurativa (HS) exists. Knowledge regarding incidence and remission rates of self\u2010reported HS is missing, but may help bridge the gap in understanding between these two phenotypes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the incidence and remission rates of self\u2010reported HS, and to what degree these are affected by sex, smoking and BMI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective cohort of 23\u2009930 Danish blood donors. Information on self\u2010reported HS, symptom\u2010localisation, sex, age, BMI and smoking status was collected at baseline and study termination. Self\u2010reported HS fulfilled clinical obligatory diagnostic criteria. Cox proportional hazards regression analyses were conducted for both incidence and remission rates providing a hazard ratio (HR) of risk for each variable in the regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Incidence rate of self\u2010reported HS was 10.8\/1000 person\u2010years (95% confidence interval (CI): 9.9\u201311.7), decreasing as a function of numbers of areas affected. Female BMI points above 25 (HR\u2009=\u20091.11, 95% CI: 1.09\u20131.13), male BMI points above 25 (HR\u2009=\u20091.07, 95% CI: 1.04\u20131.11), active smoking (HR\u2009=\u20091.72, 95% CI: 1.15\u20132.57), male sex (HR\u2009=\u20090.55, 95% CI: 0.45\u20130.67) and years of age above 25 (HR\u2009=\u20090.97, 95% CI: 0.96\u20130.97) were all statistically associated with the development of self\u2010reported HS. Remission rate of self\u2010reported HS was 256.7\/1000 person\u2010years (95% CI: 223.9\u2013292.6), decreasing as a function of numbers of affected areas. Symptoms in \u22653 areas (HR\u2009=\u20090.54, 95% CI: 0.34\u20130.85), active smoking (HR\u2009=\u20090.49, 95% CI: 0.32\u20130.76) and female weight loss (every percentage drop in BMI: HR\u2009=\u20091.07, 95% CI: 1.05\u20131.11) all significantly affected the remission rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both incidence and remission rates of self\u2010reported HS are high, indicating that many with self\u2010reported HS are unlikely to be diagnosed, as they to a higher degree experience mild transient HS symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.17857","type":"journal-article","created":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T08:39:54Z","timestamp":1638607194000},"page":"717-725","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Incidence and remission rates of self\u2010reported hidradenitis suppurativa \u2010 A prospective cohort study conducted in Danish blood donors"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0159-670X","authenticated-orcid":false,"given":"R.","family":"Kj\u00e6rsgaard Andersen","sequence":"first","affiliation":[{"name":"Department of Dermatology Zealand University Hospital Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.C.","family":"Loft","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Zealand University Hospital N\u00e6stved Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Danish Headache Center Department of Neurology Glostrup Research Institute Rigshospitalet Glostrup Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Hjalgrim","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Research Centre for Cancer Research Danish Cancer Society Statens Serum Institut Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Rostgaard","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Research Centre for Cancer Research Danish Cancer Society Statens Serum Institut Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Banasik","sequence":"additional","affiliation":[{"name":"The Novo Nordisk Foundation Center for Protein Research Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bruun","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.M.","family":"Dinh","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Statens Serum Institute Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Burgdorff","sequence":"additional","affiliation":[{"name":"Statens Serum Institute Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Erikstrup","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Aarhus 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