{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:03:31Z","timestamp":1791407011052,"version":"4.3.3"},"reference-count":29,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T00:00:00Z","timestamp":1648425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Artificial Intelligence (A.I) and deep learning\u2010based algorithms are increasingly being used in dermatology following the emergence of powerful smartphones with high\u2010resolution cameras.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To use an A.I\u2010based algorithm, validated by dermatologists, to compare the evolution of the skin ageing process among Chinese and European women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Selfie images were taken by 465\u2009587 European and 79\u2009016 Chinese women ranging from 18 to 85 and 18 to 69\u2009years old, respectively, without facial skin diseases and who had access to a smartphone with a high\u2010resolution camera (\u22654 Megapixels). The selfies were analysed by facial skin diagnostic using a smartphone application to grade the severity of 9 facial signs (including wrinkles, sagging, vascular, pigmentation signs, pores).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Wrinkles\/texture, ptosis and sagging increased linearly with age in European women compared to lower scores and more gradual increase in the younger age\u2010classes in Chinese women. In Chinese women, pigmentation signs increased regularly between 18 and 40\u2009years, plateaued between 40 and 60\u2009years, then increased in the over 60s compared to lower scores and a slower more regular increase with age in European women. Vascularization signs increased steadily with age in European women compared to no significant change in Chinese women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Marked differences were observed in the skin ageing process between European and Chinese populations, both in the prevalence of each facial ageing sign and their kinetics. Automatic grading performed on selfies and analysed by A.I is a fast and confidential method for quantifying signs of facial ageing and identifying the main issues for each population and age\u2010class, which is of practical interest, as it will allow the development of tailored prevention and therapeutic measures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.18073","type":"journal-article","created":{"date-parts":[[2022,3,13]],"date-time":"2022-03-13T04:09:21Z","timestamp":1647144561000},"page":"1136-1142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Artificial Intelligence analysis of over half a million European and Chinese women reveals striking differences in the facial skin ageing process"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1128-9535","authenticated-orcid":false,"given":"F.","family":"Flament","sequence":"first","affiliation":[{"name":"L\u2019Or\u00e9al Research and Innovation  Clichy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Jacquet","sequence":"additional","affiliation":[{"name":"Vichy International  Levallois\u2010Perret France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ye","sequence":"additional","affiliation":[{"name":"L\u2019Or\u00e9al Research and Innovation  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Amar","sequence":"additional","affiliation":[{"name":"L\u2019Or\u00e9al Research and Innovation  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Kerob","sequence":"additional","affiliation":[{"name":"Vichy International  Levallois\u2010Perret France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Jiang","sequence":"additional","affiliation":[{"name":"ModiFace \u2013 A L'Or\u00e9al Group Company  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhang","sequence":"additional","affiliation":[{"name":"ModiFace \u2013 A L'Or\u00e9al Group Company  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Kroely","sequence":"additional","affiliation":[{"name":"L\u2019Or\u00e9al CDO \u2013 Digital Service Factory  Clichy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Delaunay","sequence":"additional","affiliation":[{"name":"L\u2019Or\u00e9al Research and Innovation  Clichy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0797-6570","authenticated-orcid":false,"given":"T.","family":"Passeron","sequence":"additional","affiliation":[{"name":"Department of Dermatology Universit\u00e9 C\u00f4te d\u2019Azur CHU Nice  Nice France"},{"name":"Universit\u00e9 C\u00f4te d\u2019Azur INSERM U1065, C3M  Nice France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30226-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature21056"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(19)30333-X"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0942-0"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18880"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.101629"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12512"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12602"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12563"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12922"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature15393"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.458"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt142"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.04.026"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27145-2"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2019.08.010"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12982"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13037"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13153"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2005.06.006"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2016.05.011"},{"key":"e_1_2_8_23_1","volume-title":"Skin Aging Atlas. 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