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Here, we performed a systematic review and meta\u2010analysis to assess the prevalence of MetS among patients with psoriasis. We searched five databases from inception through September 2021 and used the Agency for Healthcare Research and Quality (AHRQ) and Newcastle\u2013Ottawa Scale (NOS) tools to assess observational study quality. Stata SE 15.1 was used to perform the data analysis. Subgroup, meta\u2010regression and sensitivity analyses were used to evaluate interstudy heterogeneity. Publication bias was evaluated using Egger's and Begg's linear tests. The global prevalence of MetS in patients with psoriasis was 32% (95% confidence interval [CI], 0.26\u20130.38). The prevalence in adults was 32% (95% CI, 0.29\u20130.36), while that in children and adolescents was 9% (95% CI, 0.00\u20130.18). Latin America had the highest prevalence of 47% (95% CI, 0.43\u20130.51), whereas North America had the lowest prevalence of 26% (95% CI, 0.16\u20130.37). Patients with psoriasis vulgaris (29%; 95% CI, 0.23\u20130.35) or severe psoriasis (37%; 95% CI, 0.27\u20130.46) had a higher prevalence of MetS than those with other psoriasis types. These findings suggest that MetS should be appropriately recognized and managed in patients with psoriasis. More population\u2010based prospective observational studies are required to elucidate the mechanisms underlying the coexistence of MetS in patients with psoriasis.<\/jats:p>","DOI":"10.1111\/jdv.18296","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T16:10:20Z","timestamp":1654531820000},"page":"1969-1979","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Global prevalence of metabolic syndrome in patients with psoriasis in the past two decades: current evidence"],"prefix":"10.1111","volume":"36","author":[{"given":"L.","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China"},{"name":"Shanghai University of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.\u2010c.","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China"},{"name":"Shanghai University of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.\u2010y.","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China"},{"name":"Institute of Dermatology Shanghai Academy of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.\u2010q.","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China"},{"name":"Institute of Dermatology Shanghai Academy of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.\u2010z.","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Dermatology The First Hospital of Jiaxing &amp; The Affiliated Hospital of Jiaxing University Jiaxing Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China"},{"name":"Shanghai University of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China"},{"name":"Institute of Dermatology Shanghai Academy of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8607-8874","authenticated-orcid":false,"given":"B.","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Shanghai Academy of Traditional Chinese Medicine Shanghai China"},{"name":"Department of Dermatology Shanghai Skin Disease Hospital Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2525-9679","authenticated-orcid":false,"given":"X.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China"},{"name":"Institute of Dermatology Shanghai Academy of Traditional Chinese Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61909-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.033217"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000455840"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01668"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003676"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.645550"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145221"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21165617"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16885"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66378-7"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/ddg.12643","article-title":"Early detection of comorbidity in psoriasis: recommendations of the National Conference on healthcare in psoriasis","volume":"13","author":"Radtke MA","year":"2015","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.2008"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-142-12_Part_2-200506211-00002"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07986.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.12.1571"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2009.00777.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.370"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03856.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2012.1714"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.365"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.100474"},{"key":"e_1_2_7_24_1","first-page":"619","article-title":"Analysis of increased prevalence of metabolic syndrome in patients with psoriasis","volume":"43","author":"Wu D","year":"2013","journal-title":"J Wenzhou Med University"},{"key":"e_1_2_7_25_1","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1111\/ddg.12193","article-title":"Metabolic syndrome in untreated patients with psoriasis: case\u2010control study. 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