{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:42Z","timestamp":1787015562791,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Psoriasis studies increasingly employ outcomes that indicate complete disease resolution, yet remission and cure are poorly defined for psoriasis. We conducted a systematic literature review to identify definitions of psoriasis remission and cure reported in the literature. Medline, EMBASE, and The Cochrane Central Register of Controlled Trials databases were searched on July 22, 2020, for full\u2010text studies providing definitions for psoriasis remission\/cure. Definitions were analysed descriptively for endpoint, time\u2010frame, on\/off treatment, patient\u2010reported outcomes, and disease domains. We identified 106 studies that provided 41 unique remission definitions. Most definitions included endpoints based on Psoriasis Area and Severity Index (PASI), such as PASI75 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200916 studies), PASI90 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910), PASI100 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910), and PASI of 0 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20093), and descriptive endpoints related to \u2018skin clearance\u2019 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200918). Few definitions specified time\u2010frame, on\/off treatment or other psoriasis\u2010related disease domains. One small consensus\u2010initiative defined drug\u2010free remission for plaque psoriasis by BSA of 0 without any therapy for at least 12\u2009months. While there is no cure for psoriasis, seven studies defined psoriasis cure using similar endpoints to those used to define remission. We identified a variety of definitions of psoriasis remission. These results will inform the development of consensus\u2010based definitions for psoriasis remission to support efforts to improve research and clinical outcomes.\n                  <\/jats:p>","DOI":"10.1111\/jdv.18477","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T03:53:47Z","timestamp":1659585227000},"page":"2291-2300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Definitions of remission in psoriasis: a systematic literature review from the National Psoriasis Foundation"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0755-3770","authenticated-orcid":false,"given":"D.M.W.","family":"Balak","sequence":"first","affiliation":[{"name":"Department of Dermatology LangeLand Hospital  Zoetermeer the Netherlands"},{"name":"Department of Dermatology Ghent University Hospital  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7724-7309","authenticated-orcid":false,"given":"L.M.","family":"Perez\u2010Chada","sequence":"additional","affiliation":[{"name":"Department of Dermatology Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2152-3567","authenticated-orcid":false,"given":"L.N.","family":"Guo","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3059-1369","authenticated-orcid":false,"given":"C","family":"Mita","sequence":"additional","affiliation":[{"name":"Countway Library of Medicine Harvard University  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0064-8707","authenticated-orcid":false,"given":"A.W.","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keck School of Medicine of University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9987-567X","authenticated-orcid":false,"given":"S.J.","family":"Bell","sequence":"additional","affiliation":[{"name":"National Psoriasis Foundation  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6468-0397","authenticated-orcid":false,"given":"G.C.","family":"Gondo","sequence":"additional","affiliation":[{"name":"National Psoriasis Foundation  Portland Oregon 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.82"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1505557"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-018-0135-1"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.11.015"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1800013"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0220868"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2019.4029"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.10.017"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18333"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70406-8"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2535"},{"key":"e_1_2_10_14_1","first-page":"2536","article-title":"Defining 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