{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:40:08Z","timestamp":1792143608917,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T00:00:00Z","timestamp":1667865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Haemosiderotic and aneurysmal dermatofibromas are uncommon and frequently misdiagnosed lesions, which can be considered as different histopathological stages of the same tumour. A dermoscopic diagnosis testing accuracy has not been performed for these tumours to date.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the diagnostic significance of dermoscopic structures and patterns associated with haemosiderotic\/ aneurysmal dermatofibromas in a large series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Dermoscopic images of histopathologically proven cases of 110 haemosiderotic\/ aneurysmal dermatofibromas and 501 other tumours were collected. The frequency, sensitivity, specificity, positive predictive value and negative predictive value of the dermoscopic structures and patterns associated with these lesions were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Haemosiderotic\/ aneurysmal dermatofibromas are mostly symmetric lesions (86.5%), and a prominent homogeneous area was present in 100% of them. The presence of vascular structures was very common (86.4%), and dotted vessels were predominant (58.2%). Shiny white structures were seen in 85.5% of lesions, while a peripheral delicate pigment network was present in 69.1%. The most significant pattern was the one composed of a prominent homogeneous area and peripheral delicate pigment network, which showed a specificity of 100% with a relatively good sensitivity (69.1%). All the patterns containing a peripheral delicate pigment network showed very good specificities, positive predictive values and negative predictive values. Those patterns without a peripheral delicate pigment network showed the highest sensitivities, but they showed a significant overlap with other tumours, mainly with melanoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dermoscopy is helpful in improving the diagnostic accuracy of haemosiderotic\/ aneurysmal dermatofibromas. However, there is a considerable dermoscopic overlap between these tumours and melanoma, specifically when the peripheral delicate pigment network is absent.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.18664","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T15:54:27Z","timestamp":1666022067000},"page":"317-327","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Dermoscopy of haemosiderotic\/aneurysmal dermatofibroma: A morphological study of 110 cases"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9573-6138","authenticated-orcid":false,"given":"Pedro","family":"Zaballos","sequence":"first","affiliation":[{"name":"Dermatology Department Hospital Sant Pau i Santa Tecla  Tarragona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1691-3280","authenticated-orcid":false,"given":"Marcial","family":"\u00c1lvarez\u2010Salafranca","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Cl\u00ednico Universitario Lozano Blesa  Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6228-7436","authenticated-orcid":false,"given":"\u00c0lex","family":"Llambrich","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitari Son Llatzer  Palma de Mallorca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6998-914X","authenticated-orcid":false,"given":"Josep","family":"Malvehy","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Cl\u00ednic  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8339-8186","authenticated-orcid":false,"given":"Rosa","family":"Taberner","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitari Son Llatzer  Palma de Mallorca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Medina","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitario de Gran Canaria \u201cDoctor Negr\u00edn\u201d  Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1413-8214","authenticated-orcid":false,"given":"Giuseppe","family":"Argenziano","sequence":"additional","affiliation":[{"name":"Dermatology Unit University of Campania  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1995-2434","authenticated-orcid":false,"given":"Luc","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Dermatology Centre Hospitalier Lyon Sud  Lyon France"},{"name":"Lyon 1 University  Lyon France"},{"name":"Lyons Cancer Research Center UMR INSERM U1052 \u2013 CNRS5286 \u2013 UCBL1  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2183-8374","authenticated-orcid":false,"given":"\u00c1ngel","family":"Pizarro","sequence":"additional","affiliation":[{"name":"Dermatology Department Cl\u00ednica Dermatol\u00f3gica Internacional  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9664-6591","authenticated-orcid":false,"given":"Luis Javier","family":"del Pozo","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitari Son Espases  Palma de Mallorca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9451-4392","authenticated-orcid":false,"given":"Jose Antonio","family":"Avil\u00e9s","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitario Gregorio Mara\u00f1\u00f3n  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Mar\u00eda","family":"Martin","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Cl\u00ednico Universitario  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isil","family":"Karaarslan","sequence":"additional","affiliation":[{"name":"Dermatology Department Medical University of Ege  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neus","family":"Guionnet","sequence":"additional","affiliation":[{"name":"Pathology Department Hospital de Sant Pau I Santa Tecla  Tarragona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0990-7608","authenticated-orcid":false,"given":"Jos\u00e9","family":"Ba\u00f1uls","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital General Universitario de Alicante, ISABIAL  Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-017-1429-6"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810415)47:8<2053::AID-CNCR2820470825>3.0.CO;2-A"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13302"},{"issue":"3","key":"e_1_2_10_5_1","first-page":"1221","article-title":"Aneurysmal dermatofibroma mimicking both clinical and dermoscopic malignant melanoma and Kaposi's sarcoma","volume":"55","author":"Morariu SH","year":"2014","journal-title":"Rom J Morphol Embryol"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.0804a19"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3315\/jdcr.2015.1198"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.1508"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01633.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20173563"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13046"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.0603a02"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1995.tb00193.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06844.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.12.038"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.2466"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13861"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.9.1120"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15093"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.11.1431"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12019"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2007.8"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.12.1485"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.07.073"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1683"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.11.021"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13092"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03283.x"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12775"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15392"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12318"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.6.824"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13150"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2018.05.007"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06617.x"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16815"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17059"},{"issue":"2","key":"e_1_2_10_38_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/ddg.14019","article-title":"Differentiation of combined nevi and melanomas: Case\u2010control study with comparative analysis of dermoscopic features","volume":"18","author":"Schweizer A","year":"2020","journal-title":"J Dtsch Dermatol Ges"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.18664","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.18664","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.18664","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T13:40:58Z","timestamp":1692711658000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.18664"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,8]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/jdv.18664"],"URL":"https:\/\/doi.org\/10.1111\/jdv.18664","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,8]]},"assertion":[{"value":"2022-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}