{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T08:42:51Z","timestamp":1761986571639,"version":"3.40.5"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,3,4]],"date-time":"2023-03-04T00:00:00Z","timestamp":1677888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vaccination of the population is required to combat the COVID\u201019 pandemic. Allergy testing could reduce anxiety towards COVID\u201019 vaccination and thereby may increase vaccination rate, however, its effectiveness remains unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and thirty prospective real\u2010life patients in need of but not daring to get vaccinated asked for allergy workup for COVID\u201019 vaccine hypersensitivity in 2021\/2022. Characterization of patients, identification of anxieties, decrease of patient's anxiety levels, overall vaccination rate and adverse reactions after vaccination were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Tested patients were characterized by being female (91.5%) and having a high rate of previous allergies (e.g. to food 55.4%, drugs 54.6%, or previous vaccinations 50%) and dermatological disease (29.2%) but not always had medical contraindications for COVID\u201019 vaccination. Sixty one patients (49.6%) were highly concerned (4\u20106, Likert scale 0\u20106) about vaccination and 47 (37.6%) expressed resolving thoughts about vaccinaion anaphylaxis (3\u20106, Likert scale 0\u20106). However only 35 patients (28.5%) were scared of getting COVID\u201019 within 2 months (4\u20136, Likert scale 0\u20136) and only 11 (9%) patients had high expectations of getting COVID\u201019 (4\u20136, Likert scale 0\u20136). Allergy testing significantly (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.01 to <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.05 respectively) reduced the median anxiety of allergic symptoms following vaccination: dyspnoea (4.2\u20133.1), to faint (3.7\u20132.7), long\u2010term consequences (3.6\u20132.2), pruritus (3.4\u20132.6), skin rash (3.3\u20132.6) and death (3.2\u20132.6). After allergy testing, most patients (108\/122, 88.5%) let themselves be vaccinated within 60\u2009days. Revaccinated patients with previous symptoms experienced a reduction of symptoms (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.05) upon revaccination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients not daring to get vaccinated have more anxiety towards vaccination than to acquire COVID\u201019. For those, allergy testing excludes vaccine allergy, and is a tool to increase vaccination willingness and thereby helps to combat vaccination hesitancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.18979","type":"journal-article","created":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T18:39:31Z","timestamp":1676745571000},"page":"1228-1235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Increasing the COVID\u201019 immunization rate through allergy testing"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1218-3399","authenticated-orcid":false,"given":"R. K.","family":"Bent","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Weinbrenner","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Faihs","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Steffens","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Nau","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Vitus","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Mathes","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Darsow","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Biedermann","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2775-3681","authenticated-orcid":false,"given":"K.","family":"Brockow","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein, Faculty of Medicine Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,3,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abn1755"},{"key":"e_1_2_11_3_1","unstructured":"Johns Hopkins University.Coronavirus Resource Center. Available from:https:\/\/coronavirus.jhu.edu. Accessed August 04 2022."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2119451"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2116597"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2022.27.18.2200322"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2022.100714"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.02.054"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14840"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15006-021-9530-6"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12044"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.06.006"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.5414\/ALX02378"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14726"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.1967"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7002e1"},{"issue":"2","key":"e_1_2_11_17_1","first-page":"125","article-title":"Behaviorally informed strategies for a national COVID\u201019 vaccine promotion program","volume":"325","author":"Volpp KG","year":"2021","journal-title":"JAMA"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9020160"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15241"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.03.041"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40629-021-00165-7"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15183"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.18176\/jiaci.0829"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2022.04.006"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.11.021"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-022-12900-y"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.03.023"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.01.022"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14112"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2014.04.004"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.770985"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2008.03184.x"},{"key":"e_1_2_11_33_1","unstructured":"World Health Organization (WHO).Ten Threats to Global Health in 2019.2019Available from:https:\/\/wwwwhoint\/news\u2010room\/spotlight\/ten\u2010threats\u2010to\u2010global\u2010health\u2010in\u20102019(accessed on 01 August 2022)."},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107724"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.18979","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdv.18979","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.18979","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T08:34:00Z","timestamp":1692520440000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.18979"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,4]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/jdv.18979"],"URL":"https:\/\/doi.org\/10.1111\/jdv.18979","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"type":"print","value":"0926-9959"},{"type":"electronic","value":"1468-3083"}],"subject":[],"published":{"date-parts":[[2023,3,4]]},"assertion":[{"value":"2022-10-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}