{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T22:31:12Z","timestamp":1788993072682,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"S6","license":[{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Blue light (BL), particularly high\u2010energy visible (HEV) light (400\u2013450\u2009nm), can cause skin damage and pigmentation. Therefore, effective sunscreens should offer photoprotection beyond ultraviolet (UV) radiation to also prevent or limit BL\u2010induced cutaneous effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the in vitro BL photostability and photoprotection properties of nine sunscreens containing the broad\u2010spectrum UV\/BL phenylene bis\u2010diphenyltriazine (PBDT or TriAsorB\u2122) filter, together with three other organic UV filters, and to assess the in vivo photoprotection level provided by two of these products against BL\u2010induced skin pigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In vitro BL photostability and photoprotection factors, comprising the percentage of BL radiation stopped by the product (%BL) and the critical wavelength extended to BL (BL\u2010CW), were determined by spectrophotometry. The in vivo photoprotection provided by two representative sunscreens (i.e. similar formulations, one non\u2010tinted and one tinted) was assessed in two open randomized studies (20 and 16 women, respectively) after exposure of two test areas (with and without sunscreen) on the back of each subject to a 412\u2010nm irradiation dose at 50\u2009J\/cm<jats:sup>2<\/jats:sup>, using instrumental and clinical measurements of skin pigmentation. The percentage sunscreen photoprotective effectiveness (%PPE) was calculated by comparing intrasubject post\u2010exposure pigmentation changes between the with and without sunscreen test areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In vitro, the nine PBDT\u2010containing products were highly photostable and had a BL\u2010CW \u2265385\u2009nm and a %BL \u226530% (range: 30%\u201350%), thus allowing effective BL photoprotection. In vivo, both representative sunscreens prevented BL\u2010induced immediate skin pigmentation (1 and 24\u2009h post\u2010exposure) with %PPE values ranging from 50.7% to 75.5% for colorimetric assessments (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and from 31.2% to 72.7% for visual scores (<jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>All PBDT\u2010containing sunscreens were considered effective at absorbing BL radiation in vitro. The two representative broad\u2010spectrum sunscreens tested in subjects significantly reduced BL\u2010induced immediate skin pigmentation following single exposure to monochromatic BL radiation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.19290","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T14:16:24Z","timestamp":1694009784000},"page":"12-21","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Broad\u2010spectrum sunscreens containing the <scp>TriAsorB\u2122<\/scp> filter: In vitro photoprotection and clinical evaluation of blue light\u2010induced skin pigmentation"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5007-1566","authenticated-orcid":false,"given":"France","family":"Boyer","sequence":"first","affiliation":[{"name":"Laboratoire Pierre Fabre Centre R&amp;D  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7852-5737","authenticated-orcid":false,"given":"C\u00e9cile","family":"Delsol","sequence":"additional","affiliation":[{"name":"Laboratoires Dermatologiques Av\u00e8ne Pierre Fabre Dermo\u2010Cosm\u00e9tique  Lavaur France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2132-4517","authenticated-orcid":false,"given":"Virginie","family":"Ribet","sequence":"additional","affiliation":[{"name":"Laboratoire Pierre Fabre Centre R&amp;D  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2463-7332","authenticated-orcid":false,"given":"Priscilla","family":"Lapalud","sequence":"additional","affiliation":[{"name":"Laboratoire Pierre Fabre Centre R&amp;D  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,6]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.476"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12736"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000517644"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000188083"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12718"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.03.115"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/php.13157"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15940"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751\u20101097.2007.00286.x"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_295_18"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.04.079"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13007"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.09.040"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43630\u2010021\u201000114\u2010x"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18196"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.08.023"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12086"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.2020.5032"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12502"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18034"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2019.01.004"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S207256"},{"key":"e_1_2_12_24_1","first-page":"22","article-title":"Are you ready to protect yourself from blue light? 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