{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T16:20:22Z","timestamp":1780503622877,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:00:00Z","timestamp":1692835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cutaneous metastasis (CM) refers to the spread of malignancy to the skin. CM is perceived as an advanced stage. It might be the first sign of a primary cancer or an indicator of recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify primary cancers associated with CMs and perform a survival analysis according to advanced stage of cutaneous metastasis at a single tertiary centre in Korea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 219 patients from Samsung Medical Center from January 2009 to April 2020 were retrospectively analysed to identify cases with biopsy\u2010proven CMs. According to advanced stage of metastasis, patients were divided into three stages, CM only (CMO), CM with lymph node metastasis (CM\/LM) and CM with distant metastasis (CM\/DM), to analyse clinical characteristics and survival rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most common CM from primary cancer was breast cancer, followed by lung cancer, stomach cancer, colorectal cancer and others. When all primary cancers were included, the median survival period was 4.82\u2009years for the CMO stage, 2.15\u2009years for the CM\/LM stage and 0.80\u2009years for the CM\/DM stage, with a tendency to deteriorate with advancing stage. At 1\u2010 and 3\u2010year after occurrence of CM, the CM\/DM stage showed a significantly poorer survival rate than the other two stages.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study showed a median survival period of 22\u2009months for CM patients overall. Breast cancer has greater accessibility to the skin than other cancers. Therefore, breast cancer can metastasize to the skin without involving lymph nodes or other sites.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.19361","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T16:53:51Z","timestamp":1689785631000},"page":"2311-2318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical characteristics and survival analysis of cutaneous metastases in a single tertiary centre in Korea"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2494-8635","authenticated-orcid":false,"given":"Dong Min","family":"Shin","sequence":"first","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeon Joo","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heeyeon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7525-4740","authenticated-orcid":false,"given":"Se Jin","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3974-1290","authenticated-orcid":false,"given":"Joonho","family":"Shim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8536-1179","authenticated-orcid":false,"given":"Jong Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"},{"name":"Department of Medical Device Management &amp; Research, SAIHST Sungkyunkwan University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0765-9812","authenticated-orcid":false,"given":"Dong\u2010Youn","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6699-5202","authenticated-orcid":false,"given":"Jihye","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,24]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Fitzpatrick's dermatology in general medicine","author":"Sewon Kang MA","year":"2019"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31823069cf"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02590.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.10.007"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_234_18"},{"key":"e_1_2_9_7_1","article-title":"Cutaneous metastases of solid tumors: demographic, clinical, and survival characteristics","volume":"13","author":"Betlloch\u2010Mas I","year":"2021","journal-title":"Cureus"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2018.08.008"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000453252"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl.2011.5.1.100"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2012.05635.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20131165"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2013.28.7.1083"},{"key":"e_1_2_9_14_1","first-page":"639","article-title":"Clinicopathological study of 43 cases of metastatic skin cancer","volume":"40","author":"Park SJLD","year":"2002","journal-title":"Korean J Dermatol"},{"key":"e_1_2_9_15_1","unstructured":"Ministry of Health and Welfare of KoreaAnnual incidence of 24 types of cancers 1999\u20102017 Korea Health Statistics.1999\u20102017"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32753"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v27.i31.5126"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13135"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000026737"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2019.05.012"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i40.11428"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-019-03079-8"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.580545"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.19361","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T13:19:47Z","timestamp":1698239987000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.19361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,24]]},"references-count":22,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/jdv.19361"],"URL":"https:\/\/doi.org\/10.1111\/jdv.19361","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,24]]},"assertion":[{"value":"2022-11-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}