{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:58:22Z","timestamp":1758707902922,"version":"3.40.5"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T00:00:00Z","timestamp":1693267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81000703","81472896"],"award-info":[{"award-number":["81000703","81472896"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK2009437"],"award-info":[{"award-number":["BK2009437"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Wide local excision (WLE) of the nail unit is widely used in treating in situ and minimally invasive malignant subungual tumours. After WLE, diverse reconstruction methods have been reported. However, the best repair method has yet to be determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the repair effects and postoperative morbidity of secondary intention healing (SIH), artificial dermis grafting combined with secondary intention healing (ADGSIH) and full\u2010thickness skin grafting (FSG) after WLE of the nail unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed 21 patients who underwent WLE of the nail unit. The re\u2010epithelializing time, functional and cosmetic outcomes, postoperative complications and patients' satisfaction were assessed from the follow\u2010up records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The FSG group showed more rapid healing and better functional and cosmetic outcomes than the SIH and ADGSIH groups. The ADGSIH and FSG groups showed significant pain relief compared to the SIH group. No serious early and late postoperative complications were reported. The median follow\u2010up period was 26\u2009months, and no recurrence was observed. All patients were satisfied with the treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>FSG after the WLE of the nail unit is a therapeutic option with convenient application, significant pain relief, rapid recovery and satisfying functional and cosmetic outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.19423","type":"journal-article","created":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T09:14:11Z","timestamp":1692350051000},"page":"2583-2588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparative efficacy of different reconstruction methods after wide local excision of the nail unit: A retrospective study"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2265-6206","authenticated-orcid":false,"given":"Fang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology The First Affiliated Hospital with Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia\u2010yi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology The First Affiliated Hospital with Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu\u2010dai","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology The First Affiliated Hospital with Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7214-1537","authenticated-orcid":false,"given":"Meng\u2010xi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology The First Affiliated Hospital with Nanjing Medical University  Nanjing 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