{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:11:54Z","timestamp":1789186314090,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T00:00:00Z","timestamp":1695340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013226","name":"Les Laboratories Pierre Fabre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is limited data about the clinical meaningfulness of the Scoring of Atopic Dermatitis (SCORAD) and Patient\u2010Oriented SCORAD (PO\u2010SCORAD), particularly in children with mild\u2010to\u2010moderate AD. Regular use of patient\u2010reported outcomes, may deliver more accurate information about the overall health status of AD patients than routine but sparse physician assessments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To confirm the correlation between SCORAD, PO\u2010SCORAD, Patient\u2010Oriented Eczema Measure (POEM) and Investigator's Global Assessment (IGA). To evaluate the interpretability and clinical usefulness of the SCORAD and PO\u2010SCORAD scores in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were drawn from a 12\u2010week randomized controlled trial in 335 children, aged 2\u20136\u2009years, with mainly mild\u2010to\u2010moderate AD. Investigators captured SCORAD and IGA at each study visit. Parents used PO\u2010SCORAD twice\u2010weekly, and POEM once\u2010weekly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were strong correlations between PO\u2010SCORAD and SCORAD (<jats:italic>r<\/jats:italic>\u2009=\u20090.874), PO\u2010SCORAD and POEM (0.734) and PO\u2010SCORAD and IGA (0.613). The best fit (\u2018<jats:italic>k<\/jats:italic>\u2019 statistic: 0.68) between SCORAD and IGA classes was noted for the following SCORAD categories: &lt;12 (clear\/almost clear); 12\u201325 (mild); and \u226525 (moderate\/severe). PO\u2010SCORAD area under the curve over 8\u2009weeks was significantly greater than that of SCORAD (<jats:italic>p<\/jats:italic>\u2009=\u20090.0002), giving a better estimate of disease severity between visits. Patients with a flare within the next 7\u2009days had significantly higher PO\u2010SCORAD scores 7\u2009days before the flare (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Moderate erythema was the most significant flare predictor (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PO\u2010SCORAD is robust and reliable and appears to warrant far greater utility in routine clinical practice than other scores. PO\u2010SCORAD, used twice\u2010weekly, may improve the management of patients with AD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.19494","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T01:07:15Z","timestamp":1693962435000},"page":"175-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The Patient\u2010Oriented Scoring of Atopic Dermatitis and SCORAD in young children: New data on interpretability and clinical usefulness"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6629-9100","authenticated-orcid":false,"given":"S.","family":"Barbarot","sequence":"first","affiliation":[{"name":"Department of Dermatology, CHU Nantes, INRAE, UMR 1280, PhAN Nantes Universit\u00e9  Nantes 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