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This international conference was designed to address prominent topics of clinical dermatology in a holistic way, allowing to articulate multiple viewpoints. Therefore, this review does not claim to be exhaustive, but is instead intended to give an overview of recent developments and ongoing controversies in the field of photoprotection. Cumulative ultraviolet radiation (UVR) exposure is the major aetiological factor in the development of photoageing, photoimunosuppression and photocarcinogenesis. UVA (320\u2013400\u2009nm) penetrates into the dermis and damages DNA and other intracellular and acellular targets primarily by generating reactive oxygen species (ROS). It is the major contributor to photoageing, characterized by fine and coarse wrinkles, dyspigmentation and loss of elasticity. UVB (290\u2013320 nm) is responsible for sunburns through direct damage to DNA by the formation of 6\u20134 cyclobutane pyrimidine dimers (CPDs) and pyrimidine 6\u20134 pyrimidone photoproducts. Both UVA and UVB exposure increase the risk of basal cell carcinoma, squamous cell carcinoma and melanoma. In recent years, visible light (VL; 400\u2013700\u2009nm) has also been implicated in the exacerbation of conditions aggravated by sun exposure such as hyperpigmentation and melasma. Photoprotection is a critical health strategy to reduce the deleterious effects of UVR and VL. Comprehensive photoprotection strategies include staying in the shade when outdoors, wearing photoprotective clothing including a wide\u2010brimmed hat, and sunglasses, and the use of sunscreen. Due to the absorption of UV filters, the safety of sunscreens has been questioned. Newer sunscreens are becoming available with filters with absorption even beyond the UV spectrum, offering enhanced protection compared with older products. Prevention of photocarcinogenesis, sun\u2010induced or sunlight\u2010exacerbated hyperpigmentary conditions and drug\u2010induced photosensitivity is an important reason for adopting comprehensive photoprotection strategies.<\/jats:p>","DOI":"10.1111\/jdv.19677","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T05:09:54Z","timestamp":1719378594000},"page":"12-20","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Photoprotection: Current developments and controversies"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7222-2951","authenticated-orcid":false,"given":"Giovanni","family":"Pellacani","sequence":"first","affiliation":[{"name":"Dermatology Clinic La Sapienza University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry W.","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Henry Ford Health  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eggert","family":"Stockfleth","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Dermatologie, Venerologie und Allergologie, St. Josef\u2010Hospital Ruhr\u2010Universit\u00e4t Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2585-6633","authenticated-orcid":false,"given":"Vincent","family":"Sibaud","sequence":"additional","affiliation":[{"name":"Department of Oncodermatology Claudius Regaud Institute and University Cancer Institute Toulouse Oncopole  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariadna Ortiz","family":"Brugu\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Oncodermatology Claudius Regaud Institute and University Cancer Institute Toulouse Oncopole  Toulouse France"},{"name":"Laboratoires Dermatologiques Av\u00e8ne Pierre Fabre Dermo\u2010Cosm\u00e9tique, Les Cauquillous  Lavaur France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6124-5122","authenticated-orcid":false,"given":"Mark\u00e9ta","family":"Saint\u00a0Aroman","sequence":"additional","affiliation":[{"name":"Medical Direction Dermo\u2010Cosm\u00e9tique &amp; 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