{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T11:19:43Z","timestamp":1784200783405,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T00:00:00Z","timestamp":1701475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005897","name":"Soci\u00e9t\u00e9 Fran\u00e7aise de Dermatologie et de Pathologie Sexuellement Transmissible","doi-asserted-by":"publisher","award":["Bourse d'aide \u00e0 la Recherche 2020 2021"],"award-info":[{"award-number":["Bourse d'aide \u00e0 la Recherche 2020 2021"]}],"id":[{"id":"10.13039\/501100005897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Strategies for the control of scabies should be adapted to local settings. Traditional communities in French Guiana have non\u2010Western conceptions of disease and health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objectives for this study were to explore knowledge, attitudes and practices to identify potential factors associated with the failure of scabies treatment in these communities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with a clinical diagnosis of scabies, seen at either the Cayenne Hospital or one of 13 health centres between 01 April 2021 and 31 August 2021, were included as participants, and were seen again after 6\u2009weeks to check for persistence of lesions. Factors associated with treatment failure were looked for both at inclusion and at 6\u2009weeks. Semi\u2010structured interviews were conducted with a diversified subsample of participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 164 participants were included in the quantitative component, and 21 were interviewed for the qualitative component. Declaring that the second treatment dose had been taken was associated with therapeutic success. Western treatments were not always affordable. Better adherence was observed with topical treatments than with oral ivermectin, whereas permethrin monotherapy was associated with failure. Scabies\u2010associated stigma was high among Amerindians and Haitians but absent in Ndjuka Maroons. Participants reported environmental disinfection as being very complex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The treatment of scabies in traditional Guianan communities may vary depending on local perceptions of galenic formulations, disease\u2010associated stigma and differences in access to health care. These factors should be taken into account when devising strategies for the control of scabies aimed at traditional communities living in remote areas, and migrant populations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.19688","type":"journal-article","created":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T19:40:19Z","timestamp":1701546019000},"page":"602-612","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Scabies in French Guiana: Quantitative and qualitative factors associated with therapeutic failure"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3695-6824","authenticated-orcid":false,"given":"R.","family":"Blaizot","sequence":"first","affiliation":[{"name":"Centre Hospitalier de Cayenne Service de Dermatologie  Cayenne French Guiana"},{"name":"Centre Hospitalier de Cayenne Inserm CIC 1424, Centre d'Investigations Cliniques  Cayenne French Guiana"},{"name":"UMR 1019 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