{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:25:56Z","timestamp":1747185956455,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lichen striatus (LS) is an acquired skin disorder with a linear pattern along Blaschko's lines. It commonly occurs in childhood, and the lesions spontaneously regress within several months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Although up to 50% of LS cases exhibit hypopigmentation that can persist for several months to years, it is unknown why LS is associated with such a high incidence of hypopigmentation compared to other inflammatory skin diseases. Therefore, this study aimed to analyse the differences in the skin microbiome between LS patients with and without hypopigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Differences in skin microbiome were analysed using whole genome sequencing of skin biopsies and subsequent bioinformatics analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Some microbes commonly found in hypopigmented skin disorders, including <jats:italic>Cutibacterium acnes<\/jats:italic>, were more abundant in patients with LS showing hypopigmentation than in those not showing hypopigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The skin microbiota may be involved in the development of hypopigmentation in LS and may be considered a treatment target to reduce LS duration and hypopigmentation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.19746","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T05:27:04Z","timestamp":1704346024000},"page":"1776-1782","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association between the skin microbiome and lichen striatus hypopigmentation: <i>Cutibacterium acnes<\/i> as a potential cause"],"prefix":"10.1111","volume":"38","author":[{"given":"Yeuni","family":"Yu","sequence":"first","affiliation":[{"name":"Biomedical Research Institute, School of Medicine Pusan National University  Yangsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3726-7652","authenticated-orcid":false,"given":"Byunghyuk","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine Pusan National University  Busan 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