{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:35:10Z","timestamp":1791264910432,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T00:00:00Z","timestamp":1703203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Psoriasis is one of the most common dermatoses associated with a variety of comorbidities. There have been some reports on its possible association with ocular disorders however dry eye syndrome (DES) in such patients has been poorly investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the frequency of DES symptoms in psoriatic patients, also regarding psoriasis severity in PASI, manifestation and therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>40 patients with psoriasis and 40 volunteers without dermatoses were enrolled in the study. They completed Ocular Surface Disease Index (OSDI) questionnaire and were objectively examined by IDRA\u00ae device to perform automatic interferometry, automatic meibography of lower eyelid glands, non\u2010invasive break\u2010up time (NIBUT), blink quality and tear meniscus height.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with psoriasis had statistically significantly thicker lipid layer (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0042 left eye,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0313 right eye) and greater loss of Meibomian glands compared to controls (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0128 left eye,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.048 right eye). The patients had lower, although insignificantly, eye blink quality and tear meniscus height than the control group, as well as shorter NIBUT and higher score in OSDI. After the division of patients into two groups\u2013with or without nails involvement\/psoriatic arthritis\/systemic treatment\u2013 we did not observe any significant differences between the groups. PASI did not correlate with any DES parameter.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This is the first study of DES symptoms with an objective IDRA\u00ae analyzer. We managed to observe that patients with psoriasis have thicker lipid layer and higher Meibomian glands' loss in lower eyelids. Based on all assessed objective and subjective parameters psoriatics do not seem to have an increased risk of DES. The presence of psoriatic arthritis or nail involvement does not seem to be a predisposing factor for DES development. PASI probably cannot be a prognostic factor for any of the DES\u2010associated parameters. Nevertheless, DES in psoriasis requires further research on bigger samples to establish reliable recommendations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.19773","type":"journal-article","created":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T02:24:36Z","timestamp":1703298276000},"page":"1522-1530","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dry eye syndrome symptoms in patients with psoriasis"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6870-1167","authenticated-orcid":false,"given":"Julia","family":"Nowowiejska","sequence":"first","affiliation":[{"name":"Department of Dermatology Medical University of Bialystok  Bia\u0142ystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata Joanna","family":"Ordon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Independent Public University Eye Hospital Medical University of Warsaw  Warsaw Poland"},{"name":"Department of Binocular Vision Pathophysiology and Strabismus Medical University of Lodz  Lodz Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Baran","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Bialystok  Bia\u0142ystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justyna","family":"Izdebska","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Independent Public University Eye Hospital Medical University of Warsaw  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bartosz","family":"Wo\u017aniak","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Independent Public University Eye Hospital Medical University of Warsaw  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz W.","family":"Kaminski","sequence":"additional","affiliation":[{"name":"Pittsburgh Heart, Lung and Blood Vascular Medicine Institute University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Szaflik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Independent Public University Eye Hospital Medical University of Warsaw  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iwona","family":"Flisiak","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Bialystok  Bia\u0142ystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20061475"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.11.058"},{"key":"e_1_2_11_4_1","first-page":"273","article-title":"Sleep disorders in psoriasis","volume":"107","author":"Nowowiejska J","year":"2020","journal-title":"Dermatol Rev"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000522167"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2017.05.006"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S228838"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-4534.337849"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2017.05.003"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2017.05.011"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2013.10.008"},{"key":"e_1_2_11_12_1","first-page":"71","article-title":"The pathophysiology, diagnosis, and treatment of dry eye disease","volume":"112","author":"Messmer EM","year":"2015","journal-title":"Dtsch Arztebl Int"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.64.1.5"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000649"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_689_19"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20180044"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1120672120969035"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000003052"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40135-013-0009-1"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e32833a8c15"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.11.060"},{"key":"e_1_2_11_22_1","first-page":"581","article-title":"Diagnosis of dry eye disease and emerging technologies","volume":"8","author":"Zeev MS","year":"2014","journal-title":"Clin Ophthalmol"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2021.05.008"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2019.05.007"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21155405"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000275"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21228772"},{"key":"e_1_2_11_28_1","first-page":"1038","article-title":"Metabolic syndrome risk factors and dry eye syndrome: a meta\u2010analysis","volume":"9","author":"Tang YL","year":"2016","journal-title":"Int J Ophthalmol"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2017-310307"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2020.1775259"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20170002"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-012-0226-4"},{"key":"e_1_2_11_33_1","first-page":"123","article-title":"Ocular manifestations in psoriasis: original research article","volume":"2","author":"Maitray A","year":"2016","journal-title":"Int J Ocul Oncol Oculoplasty"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05424.x"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-014-9950-8"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_551_22"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.14314"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2019.1577947"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.118.5.615"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.19773","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T04:09:47Z","timestamp":1732853387000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.19773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,22]]},"references-count":38,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/jdv.19773"],"URL":"https:\/\/doi.org\/10.1111\/jdv.19773","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,22]]},"assertion":[{"value":"2023-05-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}