{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:01:13Z","timestamp":1790182873922,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T00:00:00Z","timestamp":1725062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The American Joint Committee on Cancer (AJCC) method of staging melanoma is dated and inaccurate. It ignores important prognostic melanoma features, especially the patient's age. BAUSSS is more accurate in determining survival risk for primary cutaneous melanoma patients who have no clinical or imaging evidence of nodal or distant metastases. BAUSSS is an algorithm incorporating analysis of Breslow thickness, Age, Ulceration, Subtype of melanoma, Sex and Site. These are the six features from the patient history along with the details from the melanoma pathology report that are most predictive of mortality outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To develop a single\u2010page document that allows the clinician to determine BAUSSS biomarker\u2010predicted prognosis in consultation with the patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>From various data sources, we developed an algorithm to predict melanoma mortality using the BAUSSS biomarker system. The single\u2010page algorithm was made available to download at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/globalmelanoma.net\/bausss-survival-chart\">https:\/\/globalmelanoma.net\/bausss\u2010survival\u2010chart<\/jats:ext-link>, thus being readily available without charge to all clinicians and their patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>BAUSSS method of determining melanoma prognosis is more accurate and less costly than the AJCC staging system. The only surgery the patient requires is wide local excision of the primary tumour. This method of ascertaining melanoma risk does not require added surgery, costs, hospitalization, tests and anaesthesia, such as would be required if sentinel lymph node biopsy was undertaken. BAUSSS can be a useful tool in determining which primary melanoma patients are at sufficiently high risk to be considered for adjuvant drug therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We encourage clinicians to download and print in colour this single\u2010page BAUSSS mortality prediction tool, laminate it, and use it face to face with the patient in consultations. Not only will the patient be able to recognize his\/her long\u2010term prognosis but will also be able to see how their tumour severity compares with others.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.20292","type":"journal-article","created":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T08:19:10Z","timestamp":1725092350000},"page":"865-870","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["BAUSSS biomarker improves melanoma survival risk assessment"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8071-7199","authenticated-orcid":false,"given":"Anthony J.","family":"Dixon","sequence":"first","affiliation":[{"name":"Australasian College of Cutaneous Oncology  Docklands Victoria Australia"},{"name":"American Osteopathic College of Dermatology  Kirksville Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0333-2882","authenticated-orcid":false,"given":"Howard K.","family":"Steinman","sequence":"additional","affiliation":[{"name":"Campbell University School of Osteopathic Medicine  Lillington North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8645-5388","authenticated-orcid":false,"given":"Alexander","family":"Nirenberg","sequence":"additional","affiliation":[{"name":"Australasian College of Cutaneous Oncology  Docklands Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1646-2608","authenticated-orcid":false,"given":"Christos C.","family":"Zouboulis","sequence":"additional","affiliation":[{"name":"Departments of Dermatology, Venereology, Allergology and Immunology, Staedtisches Klinikum Dessau Brandenburg Medical School Theodor Fontane  Dessau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7281-2444","authenticated-orcid":false,"given":"Michael","family":"Sladden","sequence":"additional","affiliation":[{"name":"University of Tasmania  Launceston Tasmania Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalin","family":"Popescu","sequence":"additional","affiliation":[{"name":"Carol Davila University of Medicine and Pharmacy  Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4998-8713","authenticated-orcid":false,"given":"Stuart","family":"Anderson","sequence":"additional","affiliation":[{"name":"Australasian College of Cutaneous Oncology  Docklands Victoria Australia"},{"name":"Maffra Medical Group  Maffra Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8218-3896","authenticated-orcid":false,"given":"Caterina","family":"Longo","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Modena and Reggio Emilia  Modena Italy"},{"name":"Azienda Unit\u00e0 Sanitaria Locale\u2014IRCCS di Reggio Emilia Skin Cancer Center  Reggio Emilia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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