{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:01:44Z","timestamp":1792180904632,"version":"4.4.0"},"reference-count":51,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004596","name":"Empirikeion Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004596","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Glucagon\u2010like peptide 1 receptor agonists (GLP\u20101RA) are commonly used as treatment for type 2 diabetes mellitus and obesity. GLP\u20101RA have been found to be valuable therapeutic approaches not only for glucose control, but also for weight loss and cardiovascular risk reduction. It has also been established that GLP\u20101RA have immunological and anti\u2010inflammatory effects. The aim of this article was to comprehensively review the literature and to collect, analyse and quantitatively resynthesize evidence on the possible effects of GLP\u20101RA on inflammatory skin diseases. Through body weight reduction and subsequent systemic inflammation reduction, but mainly through their direct interaction with signalling pathways of inflammation and immune cells, GLP\u20101RA can improve psoriasis and hidradenitis suppurativa (HS). Clinical data of the positive effects of GLP\u20101RA in patients with psoriasis and HS are presented. Moreover, the immune cells and inflammatory pathways affected by GLP\u20101RA are discussed.<\/jats:p>","DOI":"10.1111\/jdv.20694","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T09:25:33Z","timestamp":1745918733000},"page":"2047-2055","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["The effects of GLP\u20101RA on inflammatory skin diseases: A comprehensive review"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5890-5783","authenticated-orcid":false,"given":"Ioanna A.","family":"Paschou","sequence":"first","affiliation":[{"name":"1st Department of Dermatology and Venereology \u201cAndreas Sygros\u201d Hospital, School of Medicine, National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelia","family":"Sali","sequence":"additional","affiliation":[{"name":"Endocrine 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